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Podoplanin 抗体 (AA 24-126)

PDPN 适用: 人 ELISA, IF, IHC (f), Coat 宿主: 小鼠 Monoclonal PDPN-1433 unconjugated
产品编号 ABIN6939085
发货至: 中国
  • 抗原 See all Podoplanin (PDPN) 抗体
    Podoplanin (PDPN)
    抗原表位
    • 12
    • 12
    • 8
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 24-126
    适用
    • 81
    • 22
    • 4
    • 3
    • 1
    宿主
    • 55
    • 26
    • 7
    • 5
    • 2
    • 2
    • 1
    小鼠
    克隆类型
    • 52
    • 46
    单克隆
    标记
    • 56
    • 10
    • 5
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This Podoplanin antibody is un-conjugated
    应用范围
    • 73
    • 33
    • 31
    • 28
    • 20
    • 18
    • 16
    • 8
    • 5
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    ELISA, Immunofluorescence (IF), Immunohistochemistry (Formalin-fixed Sections) (IHC (f)), Coating (Coat)
    特异性
    It recognizes a muco-protein of 38-43 kDa, which is identified as Podoplanin (PDPN). It localizes in stromal cells of peripheral lymphoid tissue and thymic epithelial cells. As a regulator of the lymphatic endothelium, podoplanin probably plays a role in maintaining the unique shape of podocytes. It is selectively expressed in lymphatic endotheliumas well as lymphoangiomas,Kaposi sarcomas,and in a subset of angiosarcomas with probable lymphatic differentiation. Recent studies have also shown podoplanin to be a highly sensitive and relatively specific marker for epithelioid mesothelioma. Therefore, it can be used in a panel to distinguish mesotheliomas or mesothelial cells from pulmonary carcinomas.
    交叉反应 (详细)
    Human,
    纯化方法
    200ug/ml of Ab Purified from Bioreactor Concentrate by Protein A/G.
    免疫原
    Recombinant human Podoplanin (PDPN) protein fragment (around aa 24-126) (exact sequence is proprietary)
    克隆位点
    PDPN-1433
    亚型
    IgG1
    Top Product
    Discover our top product PDPN Primary Antibody
  • 应用备注

    Positive Control: HeLa cells. Cervical or Lung Carcinoma.

    Known Application: ELISA (For coating, order antibody without BSA), Immunofluorescence (1-2 μg/mL), ,Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT),(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes), Optimal dilution for a specific application should be determined.

    限制
    仅限研究用
  • 浓度
    200 μg/mL
    缓冲液
    Prepared in 10 mM PBS with 0.05 % BSA and 0.05 % azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-80 °C
    储存方法
    Antibody with azide - store at 2 to 8 °C. Antibody is stable for 24 months. Non-hazardous. Also available WITHOUT BSA & azide at 1.0mg/ml.
    有效期
    24 months
  • 抗原
    Podoplanin (PDPN)
    别名
    PDPN (PDPN 产品)
    别名
    PDPN antibody, AGGRUS antibody, GP36 antibody, GP40 antibody, Gp38 antibody, HT1A-1 antibody, OTS8 antibody, PA2.26 antibody, T1A antibody, T1A-2 antibody, OTS-8 antibody, RANDAM-2 antibody, T1-alpha antibody, T1a antibody, T1alpha antibody, E11 antibody, RTI40 antibody, podoplanin antibody, PDPN antibody, Pdpn antibody
    背景
    Aggrus, Glycoprotein 36 KD, Glycoprotein 36, gp36, GP38, GP40, HT1A1, hT1alpha1, hT1alpha2, Lung type I cell membrane associated glycoprotein, Lung type I cell membrane associated glycoprotein T1A 2, OTS8, PA2.26, Pdpn, Podoplanin, PSEC0003, PSEC0025, T1-alpha, T1A, TI1A, TIA2,Podoplanin (PDPN) (Lymphatic Endothelial & Mesothelial Marker)
    Cellular localisation: Cell Surface and Cytoplasmic
    分子量
    38-43kDa
    基因ID
    10630, 468675
    UniProt
    Q86YL7
    途径
    Dicarboxylic Acid Transport
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