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LHCGR 抗体 (N-Term)

LHCGR 适用: 人 IF, FACS, IHC 宿主: 小鼠 Monoclonal LHCGR-1417 unconjugated
产品编号 ABIN6165116
发货至: 中国
  • 抗原 See all LHCGR 抗体
    LHCGR (Luteinizing Hormone/Choriogonadotropin Receptor (LHCGR))
    抗原表位
    • 20
    • 15
    • 6
    • 6
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    • 5
    • 2
    • 1
    • 1
    • 1
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    N-Term
    适用
    • 65
    • 32
    • 24
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    • 6
    • 1
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    • 1
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    宿主
    • 44
    • 25
    • 1
    小鼠
    克隆类型
    • 45
    • 25
    单克隆
    标记
    • 29
    • 5
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    • 2
    • 2
    • 2
    • 2
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    • 2
    • 1
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    This LHCGR antibody is un-conjugated
    应用范围
    • 48
    • 30
    • 26
    • 20
    • 14
    • 13
    • 13
    • 9
    • 3
    • 3
    • 2
    • 1
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    Immunofluorescence (IF), Flow Cytometry (FACS), Immunohistochemistry (IHC)
    原理
    Mouse Monoclonal anti-Luteinizing Hormone / Choriogonadotropin Receptor (LHCGR/1417), Purified, with BSA
    产品特性
    This antibody recognizes a protein of 78-85 kDa, which is identified as luteinizing hormone/choriogonadotropin receptor. Luteinizing hormone plays a role in spermatogenesis and ovulation by stimulating the testes and ovaries to produce steroids. Choriogonadotropin production in the placenta maintains estrogen and progesterone levels during the first trimester of pregnancy. Ovaries and testes abundantly express luteinizing hormone/choriogonadotropin receptor (LHCGR) as a seven transmembrane, G protein-coupled receptor glycoprotein. LHCGR influences the protective effect of pregnancy and Gonadotropin against breast cancer. The expression of LHCGR on breast carcinoma correlates in part to the degree of tumor differentiation. LHCGR -positive breast tumors occur more frequently in tumors with greater cell differentiation in premenopausal women. Primary antibodies are available purified, or with a selection of fluorescent CF® dyes and other labels. CF® dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
    纯化方法
    Purified
    免疫原
    Recombinant N-terminal fragment of human LHCGR (exact sequence is proprietary)
    克隆位点
    LHCGR-1417
    亚型
    IgG1 kappa
    Top Product
    Discover our top product LHCGR Primary Antibody
  • 应用备注
    Immunohistology (formalin) 0.5-1 μg/mL
    • Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM citrate buffer,  pH 6.0, for 10-20 min followed by cooling at RT for 20 min
    • Flow Cytometry 0.5-1 μg/million cells/0.1 mL
    • Immunofluorescence 1-2 μg/mL
    • Optimal dilution for a specific application should be determined by user
    说明

    HepG2 or Jurkat cells. Ovarian Carcinoma

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    200 μg/mL
    缓冲液
    PBS/0.05 % BSA/0.05 % azide
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • 抗原
    LHCGR (Luteinizing Hormone/Choriogonadotropin Receptor (LHCGR))
    别名
    Luteinizing Hormone / Choriogonadotropin Receptor (LHCGR 产品)
    别名
    HHG antibody, LCGR antibody, LGR2 antibody, LH/CG-R antibody, LH/CGR antibody, LHR antibody, LHRHR antibody, LSH-R antibody, ULG5 antibody, Gpcr19-rs1 antibody, LH-R antibody, Lhr antibody, LSHR antibody, lhr antibody, GTHR-II antibody, zfGTHR-II antibody, LHCGR antibody, LOC100222883 antibody, lh-r antibody, LOC100305044 antibody, luteinizing hormone/choriogonadotropin receptor antibody, luteinizing hormone/choriogonadotropin receptor L homeolog antibody, luteinizing hormone receptor antibody, LHCGR antibody, Lhcgr antibody, lhcgr antibody, lhcgr.L antibody, lhr antibody, LOC100305044 antibody
    分子量
    78-85 kDa
    基因ID
    3973, 468490
    UniProt
    P22888
    途径
    Regulation of Hormone Metabolic Process, Regulation of Hormone Biosynthetic Process, cAMP Metabolic Process, Glycosaminoglycan Metabolic Process, Regulation of Carbohydrate Metabolic Process, Autophagy, Negative Regulation of intrinsic apoptotic Signaling
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