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CD7 抗体 (CF®405S)

CD7 适用: 人 FACS, IF 宿主: 小鼠 Monoclonal T3-3A1 CF®405S
产品编号 ABIN6160294
发货至: 中国
  • 抗原 See all CD7 抗体
    CD7
    适用
    • 180
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    宿主
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    小鼠
    克隆类型
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    单克隆
    标记
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    This CD7 antibody is conjugated to CF®405S
    应用范围
    • 105
    • 67
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    Flow Cytometry (FACS), Immunofluorescence (IF)
    原理
    Mouse Monoclonal anti-CD7 (T3-3A1), CF405S Conjugate
    产品特性
    This antibody recognizes a protein of 40 kDa, identified as CD7, a member of the immunoglobulin gene superfamily. Its N-terminal amino acids 1-107 are highly homologous to Ig kappa-L chains whereas the carboxyl-terminal region of the extracellular domain is proline-rich and has been postulated to form a stalk from which the Ig domain projects. CD7 is expressed on the majority of immature and mature T-lymphocytes, and T cell leukemia. It is also found on natural killer cells, a small subpopulation of normal B cells and on malignant B cells. Cross-linking surface CD7 positively modulates T cell and NK cell activity as measured by calcium fluxes, expression of adhesion molecules, cytokine secretion and proliferation. CD7 associates directly with phosphoinositol 3'-kinase. CD7 ligation induces production of D-3 phosphoinositides and tyrosine phosphorylation. Primary antibodies are available purified, or with a selection of fluorescent CF® dyes and other labels. CF® dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
    免疫原
    Human T cells
    克隆位点
    T3-3A1
    亚型
    IgG1 kappa
    Top Product
    Discover our top product CD7 Primary Antibody
  • 应用备注
    Immunofluorescence 0.5-1 μg/mL
    • Flow Cytometry 0.5-1 μg/million cells/0.1 mL
    • Optimal dilution for a specific application should be determined by user
    说明

    Jurkat, HUT-78, Molt-4, CEM cells, or human peripheral blood lymphocytes. Lymph node and tonsil.

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    100 μg/mL
    缓冲液
    PBS/0.1 % BSA/0.05 % azide
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Protect from light
  • 抗原
    CD7
    别名
    CD7 (CD7 产品)
    别名
    GP40 antibody, LEU-9 antibody, TP41 antibody, Tp40 antibody, CD7 molecule antibody, CD7 antigen antibody, Cd7 molecule antibody, CD7 antibody, Cd7 antibody
    分子量
    40 kDa
    基因ID
    924, 186820
    UniProt
    P09564
    途径
    Cell-Cell Junction Organization
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