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CD7 抗体

CD7 适用: 人 FACS, WB, IP, IHC (p) 宿主: 小鼠 Monoclonal MEM-186 unconjugated
产品编号 ABIN94218
发货至: 中国
  • 抗原 See all CD7 抗体
    CD7
    适用
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    宿主
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    小鼠
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    • 1
    单克隆
    标记
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    This CD7 antibody is un-conjugated
    应用范围
    • 111
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    Flow Cytometry (FACS), Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    特异性
    The antibody MEM-186 reacts with an extracellular epitope of CD7, a 40 kD type I transmembrane glycoprotein expressed on peripheral blood T lymphocytes, NK-cells, hematopoietic progenitors, monocytes (weakly) and also on acute lymphocytic leukemia.
    交叉反应 (详细)
    Human
    纯化方法
    Purified by protein-A affinity chromatography.
    纯度
    > 95 % (by SDS-PAGE)
    免疫原
    Human acute myelogenous leukaemia cell line KG-1.
    克隆位点
    MEM-186
    亚型
    IgG1
    Top Product
    Discover our top product CD7 Primary Antibody
  • 应用备注
    Immunohistochemistry (paraffin sections): Recommended dilution: 5 μg/mL, positive tissue: spleen.
    Flow cytometry: Recommended dilution: 2 μg/mL.
    Western blotting: Non-reducing conditions.
    限制
    仅限研究用
  • 浓度
    1 mg/mL
    缓冲液
    Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Do not freeze.
    储存条件
    4 °C
    储存方法
    Store at 2-8°C. Do not freeze.
  • Rappl, Riet, Awerkiew, Schmidt, Hombach, Pfister, Abken: "The CD3-zeta chimeric antigen receptor overcomes TCR Hypo-responsiveness of human terminal late-stage T cells." in: PLoS ONE, Vol. 7, Issue 1, pp. e30713, (2012) (PubMed).

  • 抗原
    CD7
    别名
    CD7 (CD7 产品)
    别名
    GP40 antibody, LEU-9 antibody, TP41 antibody, Tp40 antibody, CD7 molecule antibody, CD7 antigen antibody, Cd7 molecule antibody, CD7 antibody, Cd7 antibody
    背景
    CD7 Molecule,CD7, also known as gp40, is a member of the immunoglobulin superfamily found on T cells, NK cells, thymocytes, hematopoietic progenitors, and monocytes (weakly). CD7 is also expressed on acute lymphocytic leukemia (ALL). CD7 crosslinking induces a calcium flux in T lymphocytes, presumably as a result of cytoplasmic domain association with PI3-kinase. CD7 co-stimulation can induce cytokine secretion and modulate cellular adhesion. A ligand of CD7, epithelial cell secreted protein K12, is produced in thymus to regulate thymocyte signaling and cytokine release. In lung microvascular endothelial cells CD7 serves as an IgM Fc receptor. Expression of CD7 is an important marker used in leukemia diagnostics.,GP40, TLA, TP41, LEU-9
    基因ID
    924
    UniProt
    P09564
    途径
    Cell-Cell Junction Organization
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