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RORC 抗体 (Internal Region)

RORC 适用: 人, 小鼠, Cow, 犬 WB, EIA 宿主: 山羊 Polyclonal unconjugated
产品编号 ABIN615977
发货至: 中国
  • 抗原 See all RORC 抗体
    RORC (RAR-Related Orphan Receptor C (RORC))
    抗原表位
    • 16
    • 7
    • 7
    • 6
    • 6
    • 6
    • 5
    • 5
    • 4
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 200-212, Internal Region
    适用
    • 97
    • 54
    • 23
    • 9
    • 8
    • 8
    • 6
    • 6
    • 6
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    人, 小鼠, Cow, 犬
    宿主
    • 80
    • 17
    • 2
    • 1
    • 1
    山羊
    克隆类型
    • 83
    • 18
    多克隆
    标记
    • 53
    • 7
    • 5
    • 5
    • 5
    • 5
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    This RORC antibody is un-conjugated
    应用范围
    • 80
    • 37
    • 24
    • 24
    • 15
    • 13
    • 11
    • 4
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Enzyme Immunoassay (EIA)
    序列
    CHLEYSPERG KAE
    特异性
    This antibody is expected to recognize both reported isoforms (NP_005051.2, NP_001001523.1).
    交叉反应 (详细)
    Species reactivity (expected):Mouse, Canine (Dog) and Cow.
    Species reactivity (tested):Human.
    纯化方法
    Ammonium Sulphate Precipitation followed by antigen Affinity Chromatography using the immunizing peptide.
    免疫原
    Peptide with sequence from the internal region of the protein sequence according to NP_005051.2, NP_001001523.1. Genename: RORC
    Top Product
    Discover our top product RORC Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 浓度
    0.5 mg/mL
    缓冲液
    Tris saline, pH 7.3 containing 0.02 % Sodium Azide as preservative and 0.5 % BSA as stabilizer.
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原
    RORC (RAR-Related Orphan Receptor C (RORC))
    别名
    ROR-gamma / RORC (RORC 产品)
    别名
    NR1F3 antibody, RORG antibody, RZR-GAMMA antibody, RZRG antibody, TOR antibody, Nr1f3 antibody, RORgamma antibody, Thor antibody, RAR related orphan receptor C antibody, RAR-related orphan receptor C antibody, RAR-related orphan receptor gamma antibody, RORC antibody, Rorc antibody
    背景
    ROR-gamma is a 560 amino acid novel DNA-binding transcription factor belonging to the ROR/RZR orphan nuclear receptor subfamily. The specific functions of this protein are not known. However, reports suggest that this protein is a ligand activated transcription factor and may be essential for lymphoid organogenesis (lymph nodes and Peyer's patches) and may play an important regulatory role in controlling apoptosis during thymopoiesis. ROR-gamma inhibits the expression of Fas ligand and IL2 and directs the differentiation program of proinflammatory IL-17+ T helper cells. ROR-gamma shares 50 to 51 % sequence identity with RORA and RORB and is 88 % identical to mouse ROR-gamma. It is highly expressed in skeletal muscle and at lower levels in various other tissues.Synonyms: NR1F3, Nuclear receptor ROR-gamma, Nuclear receptor RZR-gamma, Nuclear receptor subfamily 1 group F member 3, RORG, RZRG, Retinoid-related orphan receptor-gamma
    基因ID
    6097
    NCBI登录号
    NP_001001523
    UniProt
    P51449
    途径
    Nuclear Receptor Transcription Pathway, Steroid Hormone Mediated Signaling Pathway
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