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RORC 抗体

RORC 适用: 人, 小鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7251244
发货至: 中国
  • 抗原 See all RORC 抗体
    RORC (RAR-Related Orphan Receptor C (RORC))
    适用
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    人, 小鼠
    宿主
    • 79
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    克隆类型
    • 82
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    多克隆
    标记
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    This RORC antibody is un-conjugated
    应用范围
    • 79
    • 36
    • 24
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    • 15
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    • 11
    • 4
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    Western Blotting (WB), ELISA
    产品特性
    Polyclonal Antibody
    纯化方法
    Affinity purification
    免疫原
    Synthesized peptide derived from the Internal region of human RORC
    亚型
    IgG
    Top Product
    Discover our top product RORC Primary Antibody
  • 应用备注
    WB 1:500-1:2000, ELISA 1:40000
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    PBS with 0.02 % sodium azide, 0.5 % BSA and 50 % glycerol, pH 7.4
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原
    RORC (RAR-Related Orphan Receptor C (RORC))
    别名
    RORC (RORC 产品)
    别名
    NR1F3 antibody, RORG antibody, RZR-GAMMA antibody, RZRG antibody, TOR antibody, Nr1f3 antibody, RORgamma antibody, Thor antibody, RAR related orphan receptor C antibody, RAR-related orphan receptor C antibody, RAR-related orphan receptor gamma antibody, RORC antibody, Rorc antibody
    背景
    The protein encoded by this gene is a DNA-binding transcription factor and is a member of the NR1 subfamily of nuclear hormone receptors. The specific functions of this protein are not known, however, studies of a similar gene in mice have shown that this gene may be essential for lymphoid organogenesis and may play an important regulatory role in thymopoiesis. In addition, studies in mice suggest that the protein encoded by this gene may inhibit the expression of Fas ligand and IL2. Two transcript variants encoding different isoforms have been found for this gene.RORC (RAR Related Orphan Receptor C) is a Protein Coding gene. Diseases associated with RORC include Immunodeficiency 42 and Anus Cancer. Among its related pathways are Circadian rythm related genes and Innate Immune System. GO annotations related to this gene include transcription factor activity, sequence-specific DNA binding and steroid hormone receptor activity. An important paralog of this gene is RORA.
    分子量

    Observed_MW: 58 kDa

    Calculated_MW: 58 kDa

    UniProt
    P51449
    途径
    Nuclear Receptor Transcription Pathway, Steroid Hormone Mediated Signaling Pathway
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