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PD-1 抗体 (CF®405S)

PDCD1 适用: 人 FACS, IF, IHC (f) 宿主: 小鼠 Monoclonal PDCD1-922 CF®405S
产品编号 ABIN6158432
发货至: 中国
  • 抗原 See all PD-1 (PDCD1) 抗体
    PD-1 (PDCD1) (Programmed Cell Death 1 (PDCD1))
    适用
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    小鼠
    克隆类型
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    单克隆
    标记
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    This PD-1 antibody is conjugated to CF®405S
    应用范围
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    Flow Cytometry (FACS), Immunofluorescence (IF), Immunohistochemistry (Formalin-fixed Sections) (IHC (f))
    原理
    Mouse Monoclonal anti-PD1 / PDCD1 / CD279 (PDCD1/922), CF405S Conjugate
    产品特性
    PDCD-1 (programmed cell death-1 protein), also designated CD279, is a type I transmembrane receptor and a member of the immunoglobin gene superfamily. It is expressed on activated T-cells, B-cells, and myeloid cells. Anti-PDCD-1 is a marker of angioimmunoblastic lymphoma and suggests a unique cell of origin for this neoplasm. Unlike CD10 and BCL6, PDCD-1 is expressed by few B-cells, so anti-PDCD-1 may be a more specific and useful diagnostic marker in angioimmunoblastic lymphoma. In addition, PDCD-1 expression provides evidence that angioimmunoblastic lymphoma is a neoplasm derived from germinal center-associated T-cells. Primary antibodies are available purified, or with a selection of fluorescent CF® dyes and other labels. CF® dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
    免疫原
    Recombinant full-length human PDCD1 protein
    克隆位点
    PDCD1-922
    亚型
    IgG1 kappa
    Top Product
    Discover our top product PDCD1 Primary Antibody
  • 应用备注
    Immunohistology formalin-fixed 0.5-1 μg/mL
    • Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM Tris with 1 mM EDTA,  pH 9.0, for 10-20 min followed by cooling at RT for 20 minutes
    • Flow Cytometry 0.5-1 μg/million cells/0.1 mL
    • Immunofluorescence 1-2 μg/mL
    • Optimal dilution for a specific application should be determined by user
    说明

    TY cells or Tonsil.

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    100 μg/mL
    缓冲液
    PBS/0.1 % BSA/0.05 % azide
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Protect from light
  • 抗原
    PD-1 (PDCD1) (Programmed Cell Death 1 (PDCD1))
    别名
    PD1 / PDCD1 / CD279 (PDCD1 产品)
    别名
    CD279 antibody, PD-1 antibody, PD1 antibody, SLEB2 antibody, hPD-1 antibody, hPD-l antibody, Ly101 antibody, Pdc1 antibody, programmed cell death 1 antibody, PDCD1 antibody, Pdcd1 antibody
    背景
    CD279, hPD-1, hSLE1, PD1, PDCD1, Programmed Cell Death Protein 1, Protein PD-1, SLEB2, Systemic lupus erythematosus susceptibility 2
    分子量
    55 kDa
    基因ID
    5133, 158297
    UniProt
    Q15116
    途径
    Cancer Immune Checkpoints
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