DNASE1 抗体 (AA 1-252)
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- 抗原 See all DNASE1 抗体
- DNASE1 (Deoxyribonuclease I (DNASE1))
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抗原表位
- AA 1-252
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This DNASE1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 特异性
- This antibody recognizes Deoxyribonuclease I (DNASE1).
- 交叉反应 （详细）
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Species reactivity (expected):Rabbit (81 %), Dogs (81 %).
Species reactivity (tested):Human. - 纯化方法
- Immunoaffinity Chromatography
- 免疫原
- Recombinant protein fragment containing a sequence corresponding to a region within amino acids 1 and 252 of DNase I. Genename: DNASE1
- Top Product
- Discover our top product DNASE1 Primary Antibody
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anti-Deoxyribonuclease I (DNASE1) (AA 19-259) antibody
DNASE1 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Deoxyribonuclease I (DNASE1) (AA 22-282) antibodyDNASE1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Deoxyribonuclease I (DNASE1) antibodyDNASE1 适用: 人 WB, ICC, IF, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Deoxyribonuclease I (DNASE1) (AA 1-252) antibodyDNASE1 适用: 人 WB, IHC, ICC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Deoxyribonuclease I (DNASE1) (AA 19-259) antibodyDNASE1 适用: 人 WB, IHC, IP, ICC 宿主: 小鼠 Monoclonal 2-1# unconjugated
anti-Deoxyribonuclease I (DNASE1) (AA 78-231) antibodyDNASE1 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Deoxyribonuclease I (DNASE1) (AA 87-121) antibodyDNASE1 适用: 人, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal RB49355 unconjugated
anti-Deoxyribonuclease I (DNASE1) antibodyDNASE1 适用: 大鼠, 小鼠 IF 宿主: 兔 Polyclonal unconjugated
anti-Deoxyribonuclease I (DNASE1) (N-Term) antibodyDNASE1 适用: 人, 大鼠, Cow WB 宿主: 兔 Polyclonal unconjugated
anti-Deoxyribonuclease I (DNASE1) (AA 19-259) antibodyDNASE1 适用: 人 WB, IHC, IP, ICC 宿主: 小鼠 Monoclonal 7# unconjugated
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1.0 mg/mL
- 缓冲液
- 0.1 M Tris-glycine, pH 7.0 containing 10 % Glycerol and 0.01 % Thimerosal
- 储存液
- Thimerosal (Merthiolate)
- 注意事项
- This product contains thimerosal (merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freezing and thawing.
- 储存条件
- -20 °C
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- 抗原
- DNASE1 (Deoxyribonuclease I (DNASE1))
- 别名
- Deoxyribonuclease-1 (DNASE1 产品)
- 别名
- LOC397802 antibody, DNL1 antibody, DRNI antibody, AI788650 antibody, DNaseI antibody, Dnl1 antibody, dnase1-A antibody, zgc:92440 antibody, DNase I antibody, deoxyribonuclease 1 antibody, deoxyribonuclease I antibody, deoxyribonuclease I L homeolog antibody, Deoxyribonuclease I antibody, endA antibody, LOC397802 antibody, DNASE1 antibody, Dnase1 antibody, dnase1.L antibody, dnase1 antibody, CpipJ_CPIJ011184 antibody, CpipJ_CPIJ011185 antibody, CpipJ_CPIJ011186 antibody, CpipJ_CPIJ011187 antibody, CpipJ_CPIJ011190 antibody, CpipJ_CPIJ017803 antibody, Desal_1409 antibody, MPET_RS05255 antibody, METEV_RS02275 antibody, Plabr_0631 antibody
- 背景
- Deoxyribonuclease I (EC 3.1.21.1) gene is approximately 3.2 kb long with 9 exons separated by 8 introns. In the form of a bovine pancreatic enzyme preparation, it occupies an important place in the history of protein chemistry and enzymology: it was the first enzyme to be recognized as specific for DNA, it was the first DNase to be crystallized, and it was the first DNase for which a specific protein inhibitor was characterized. DNase I is a Ca2+ and Mg2+ dependant endonuclease. DNase I is synthesized in the pancreas and stored in zymogen granules. It has been used to reduce the viscosity of cystic fibrosis sputum. A DNase I-like enzyme appears to catalyze the degradation of chromatin to oligo- and mononucleosomes during apoptosis. A recent study has demonstrated an endonuclease with activity and antigenicity indistinguishable from DNase I in thymocytes, cells susceptible to apoptosis. DNase I is an endonuclease that hydrolyzes double-stranded or single stranded DNA preferentially at sites adjacent to pyrimidine nucleotides. The product of hydrolysis is a complex mixture of 5'-phosphate mononucleotides and oligonucleotides. In the presence of Mg ion, DNase I attacks each strand of DNA independently and the cleavage sites are random.Synonyms: DNASE1, DNL1, DNase I, DRNI, Deoxyribonuclease I
- 基因ID
- 1773
- NCBI登录号
- NP_005214
- UniProt
- P24855
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