XPC 抗体 (AA 700-940)
(1 reference)Quick Overview for XPC 抗体 (AA 700-940) (ABIN6150295)
抗原
See all XPC 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 700-940
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序列
- GEVPYKMVKG FSNRARKARL AEPQLREEND LGLFGYWQTE EYQPPVAVDG KVPRNEFGNV YLFLPSMMPI GCVQLNLPNL HRVARKLDID CVQAITGFDF HGGYSHPVTD GYIVCEEFKD VLLTAWENEQ AVIERKEKEK KEKRALGNWK LLAKGLLIRE RLKRRYGPKS EAAAPHTDAG GGLSSDEEEG TSSQAEAARI LAASWPQNRE DEEKQKLKGG PKKTKREKKA AASHLFPFEQ L
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交叉反应
- 人
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产品特性
- Polyclonal Antibodies
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免疫原
- Recombinant fusion protein containing a sequence corresponding to amino acids 700-940 of human XPC (NP_004619.3).
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亚型
- IgG
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anti-Xeroderma Pigmentosum, Complementation Group C (XPC) (C-Term) antibody
XPC 适用: 人 WB, ICC, IHC (p), IF 宿主: 兔 Polyclonal unconjugated
anti-Xeroderma Pigmentosum, Complementation Group C (XPC) antibodyXPC 适用: 人 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Xeroderma Pigmentosum, Complementation Group C (XPC) (AA 141-250) antibodyXPC 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 6D11 unconjugated
anti-Xeroderma Pigmentosum, Complementation Group C (XPC) (AA 734-933) antibodyXPC 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Xeroderma Pigmentosum, Complementation Group C (XPC) (AA 734-933) antibodyXPC 适用: 大鼠 FACS 宿主: 兔 Polyclonal unconjugated
anti-Xeroderma Pigmentosum, Complementation Group C (XPC) antibodyXPC 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Xeroderma Pigmentosum, Complementation Group C (XPC) antibodyXPC 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Xeroderma Pigmentosum, Complementation Group C (XPC) antibody (HRP)XPC 适用: 人 WB, ELISA, IHC, IHC (p) 宿主: 兔 Polyclonal HRP
anti-Xeroderma Pigmentosum, Complementation Group C (XPC) antibody (FITC)XPC 适用: 人 WB, ELISA, IHC, IHC (p) 宿主: 兔 Polyclonal FITC
anti-Xeroderma Pigmentosum, Complementation Group C (XPC) (AA 141-250) antibodyXPC 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
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应用备注
- WB,1:500 - 1:2000,IHC,1:50 - 1:100,IP,1:50 - 1:100
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说明
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HIGH QUALITY
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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: "Identification of four novel XPC mutations in two xeroderma pigmentosum complementation group C patients and functional study of XPC Q320X mutant." in: Gene, Vol. 628, pp. 162-169, (2017) (PubMed).
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: "Identification of four novel XPC mutations in two xeroderma pigmentosum complementation group C patients and functional study of XPC Q320X mutant." in: Gene, Vol. 628, pp. 162-169, (2017) (PubMed).
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- XPC (Xeroderma Pigmentosum, Complementation Group C (XPC))
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别名
- XPC
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背景
- This gene encodes a component of the nucleotide excision repair (NER) pathway. There are multiple components involved in the NER pathway, including Xeroderma pigmentosum (XP) A-G and V, Cockayne syndrome (CS) A and B, and trichothiodystrophy (TTD) group A, etc. This component, XPC, plays an important role in the early steps of global genome NER, especially in damage recognition, open complex formation, and repair protein complex formation. Mutations in this gene or some other NER components result in Xeroderma pigmentosum, a rare autosomal recessive disorder characterized by increased sensitivity to sunlight with the development of carcinomas at an early age. Alternatively spliced transcript variants have been found for this gene.,XPC,RAD4,XP3,XPCC,p125,Epigenetics & Nuclear Signaling,DNA Damage & Repair,XPC
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分子量
- 15 kDa/101 kDa/105 kDa
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基因ID
- 7508
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UniProt
- Q01831
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途径
- p53 Pathway, DNA Damage Repair
抗原
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