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RECQL2 抗体 (AA 1223-1432)

This anti-RECQL2 antibody is a 兔 多克隆 antibody detecting RECQL2 in WB. Suitable for 人.
产品编号 ABIN6150263
发货至: 中国

Quick Overview for RECQL2 抗体 (AA 1223-1432) (ABIN6150263)

抗原

See all RECQL2 (WRN) 抗体
RECQL2 (WRN) (Werner syndrome RecQ like helicase (WRN))

适用

  • 39
  • 2
  • 1

宿主

  • 32
  • 10

克隆类型

  • 31
  • 11
多克隆

标记

  • 28
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  • 1
  • 1
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This RECQL2 antibody is un-conjugated

应用范围

  • 32
  • 18
  • 11
  • 10
  • 6
  • 4
  • 4
  • 3
  • 1
  • 1
Western Blotting (WB)
  • 抗原表位

    • 7
    • 4
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    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
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    • 1
    • 1
    • 1
    AA 1223-1432

    序列

    CQTNSVQTDL FSSTKPQEEQ KTSLVAKNKI CTLSQSMAIT YSLFQEKKMP LKSIAESRIL PLMTIGMHLS QAVKAGCPLD LERAGLTPEV QKIIADVIRN PPVNSDMSKI SLIRMLVPEN IDTYLIHMAI EILKHGPDSG LQPSCDVNKR RCFPGSEEIC SSSKRSKEEV GINTETSSAE RKRRLPVWFA KGSDTSKKLM DKTKRGGLFS

    交叉反应

    产品特性

    Polyclonal Antibodies

    免疫原

    Recombinant fusion protein containing a sequence corresponding to amino acids 1223-1432 of human WRN (NP_000544.2).

    亚型

    IgG
  • 应用备注

    WB,1:200 - 1:1000

    说明

    HIGH QUALITY

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原

    RECQL2 (WRN) (Werner syndrome RecQ like helicase (WRN))

    别名

    WRN

    背景

    This gene encodes a member of the RecQ subfamily and the DEAH (Asp-Glu-Ala-His) subfamily of DNA and RNA helicases. DNA helicases are involved in many aspects of DNA metabolism, including transcription, replication, recombination, and repair. This protein contains a nuclear localization signal in the C-terminus and shows a predominant nucleolar localization. It possesses an intrinsic 3' to 5' DNA helicase activity, and is also a 3' to 5' exonuclease. Based on interactions between this protein and Ku70/80 heterodimer in DNA end processing, this protein may be involved in the repair of double strand DNA breaks. Defects in this gene are the cause of Werner syndrome, an autosomal recessive disorder characterized by premature aging.,WRN,RECQ3,RECQL2,RECQL3,Epigenetics & Nuclear Signaling,DNA Damage & Repair,Cell Biology & Developmental Biology,Apoptosis,WRN

    分子量

    162 kDa

    基因ID

    7486

    UniProt

    Q14191

    途径

    DNA Damage Repair
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