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p53 抗体 (AA 1-100)

Name: p53 抗体 (AA 1-100)
Brand: antibodies-online
SKU: ABIN6149405
Availability: OutOfStock

This anti-p53 antibody is a 兔多克隆 antibody detecting p53 in WB, IHC 和 IP. Suitable for 人. This Primary Antibody has been cited in 5+ publications.

Western blot analysis of extracts of various cell lines, using TP53 antibody. (p53 抗体 (AA 1-100))

Immunoprecipitation analysis of 150ug extracts of A549 cells using 3ug TP53 antibody. (p53 抗体 (AA 1-100))

Immunohistochemistry of paraffin-embedded rat ovary using TP53 antibody. (p53 抗体 (AA 1-100))

IHC (p)

Immunohistochemistry of paraffin-embedded human breast cancer using TP53 antibody. (p53 抗体 (AA 1-100))

IHC (p)

Immunohistochemistry of paraffin-embedded human gastric cancer using TP53 antibody. (p53 抗体 (AA 1-100))

IHC (p)

Immunohistochemistry of paraffin-embedded human lung cancer using TP53 antibody. (p53 抗体 (AA 1-100))

IHC (p)

6 images

(5 references)

产品编号 ABIN6149405

发货至: 中国

Datasheet as PDF

Quick Overview for p53 抗体 (AA 1-100) (ABIN6149405)

抗原

See all p53 (TP53) 抗体

p53 (TP53) (Tumor Protein P53 (TP53))

适用

人

宿主

兔

克隆类型

多克隆

标记

This p53 antibody is un-conjugated

应用范围

Western Blotting (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP)

Discover our top product TP53 Primary Antibody

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AA 1-100

序列

EPPEAGSEYT TIHYKYMCNS SCMGGMNRRP ILTIITLEDS SGNLLGRDSF EVRVCACPGR DRRTEEENFR KKEVLCPELP PGSAKRALPT CTSASPPQKK KPLDGEYFTL KIRGRKRFEM FRELNEALEL KDAHATEESG DSRAHSSYLK TKKGQSTSRH KKTMVKKVGP DSD

交叉反应

人, 小鼠, 大鼠

产品特性

Polyclonal Antibodies

免疫原

A synthetic peptide corresponding to a sequence within amino acids 1-100 of human p53 (NP_000537.3).

亚型

IgG
anti-Tumor Protein P53 (TP53) (pSer392) antibody
TP53 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated

anti-Tumor Protein P53 (TP53) antibody
KO Validated TP53 适用: 人 WB, IF, IHC (p), IP, ICC, ChIP 宿主: 兔 Polyclonal unconjugated

anti-Tumor Protein P53 (TP53) (N-Term) antibody
TP53 适用: 人 WB, IF, IHC (p), IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-Tumor Protein P53 (TP53) (AA 301-393) antibody
TP53 适用: 人, 小鼠, 大鼠, 山羊 WB, ELISA, FACS, IHC (p), ICC, IF (p), IF (cc), IHC (fro) 宿主: 兔 Polyclonal unconjugated

anti-Tumor Protein P53 (TP53) (pSer33) antibody
TP53 适用: 人, 小鼠, 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated

anti-Tumor Protein P53 (TP53) (AA 94-201) antibody
TP53 适用: 人 WB, ELISA, IF, IHC (p), IP 宿主: 小鼠 Monoclonal 2C3 unconjugated

anti-Tumor Protein P53 (TP53) (AA 94-201) antibody
TP53 适用: 人 WB, ELISA, IHC (p), PLA, RNAi 宿主: 小鼠 Monoclonal 2C11 unconjugated

anti-Tumor Protein P53 (TP53) (pSer20) antibody
TP53 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated

anti-Tumor Protein P53 (TP53) (pSer15) antibody
TP53 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-Tumor Protein P53 (TP53) (acLys319) antibody
TP53 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated

应用备注

WB,1:3000 - 1:6000,IHC,1:50 - 1:200,IP,1:20 - 1:50

说明

HIGH QUALITY

限制

仅限研究用
状态

Liquid

缓冲液

PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

储存条件

-20 °C

储存方法

Store at -20°C. Avoid freeze / thaw cycles.
Huang, Cui, Chen, Yang, Lian, Liu, Su, Liu, Wang, Hu, Ouyang, Li, Lu: "NVP-BEZ235 synergizes cisplatin sensitivity in osteosarcoma." in: Oncotarget, Vol. 9, Issue 12, pp. 10483-10496, (2018) (PubMed).

Huang, Zhou, He, Ke, Wen, Zou, Chen: "Hyperthermia enhances 17-DMAG efficacy in hepatocellular carcinoma cells with aggravated DNA damage and impaired G2/M transition." in: Scientific reports, Vol. 6, pp. 38072, (2018) (PubMed).

Zhang, Cui, Wang, Zhao, Hou, Zeng, Zhang, Yu, Zhao, Nie, Chen, Wang, Liu: "Autophagy regulates high concentrations of iodide-induced apoptosis in SH-SY5Y cells." in: Toxicology letters, Vol. 284, pp. 129-135, (2018) (PubMed).

Meng, Song, Wang, Li, Liu, Cui: "Propofol induces proliferation partially via downregulation of p53 protein and promotes migration via activation of the Nrf2 pathway in human breast cancer cell line MDA-MB-231." in: Oncology reports, Vol. 37, Issue 2, pp. 841-848, (2017) (PubMed).

Cai, Huang, Luo, Yang, Zhang, Liu, Lin, Xie, Wang: "Nupr1/Chop signal axis is involved in mitochondrion-related endothelial cell apoptosis induced by methamphetamine." in: Cell death & disease, Vol. 7, pp. e2161, (2016) (PubMed).
抗原

p53 (TP53) (Tumor Protein P53 (TP53))

别名

TP53

背景

This gene encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains. The encoded protein responds to diverse cellular stresses to regulate expression of target genes, thereby inducing cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. Mutations in this gene are associated with a variety of human cancers, including hereditary cancers such as Li-Fraumeni syndrome. Alternative splicing of this gene and the use of alternate promoters result in multiple transcript variants and isoforms. Additional isoforms have also been shown to result from the use of alternate translation initiation codons from identical transcript variants (PMIDs: 12032546, 20937277).,BCC7,LFS1,P53,TRP53,p53,TP53,BMFS5,Epigenetics & Nuclear Signaling,Transcription Factors,DNA Damage & Repair,Cancer,Tumor suppressors,p53 pathway,Signal Transduction,PI3K-Akt Signaling Pathway,ErbB-HER Signaling Pathway,MAPK-JNK Signaling Pathway,MAPK-P38 Signaling Pathway,Cell Biology & Developmental Biology,Apoptosis,Mitochondrial Control of Apoptosis,Cell Cycle,Cell cycle inhibitors,G1/S Checkpoint,G2/M DNA Damage Checkpoint,Endocrine & Metabolism,AMPK Signaling Pathway,Warburg Effect,Neuroscience,Neurodegenerative Diseases,TP53

分子量

43 kDa

基因ID

7157

UniProt

P04637

途径

p53 Pathway, MAPK Pathway, PI3K-Akt Signaling, Apoptosis, AMPK Signaling, Chromatin Binding, ER-Nucleus Signaling, Positive Regulation of Endopeptidase Activity, Hepatitis C, Protein targeting to Nucleus, Autophagy, Warburg Effect