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FGFR1 抗体 (C-Term)

The 山羊 多克隆 anti-FGFR1 antibody (ABIN614919) specifically detects FGFR1 in WB, IHC (p) 和 EIA. The antibody is reactive with 人, Cow 和 犬 samples.
产品编号 ABIN614919
发货至: 中国
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Quick Overview for FGFR1 抗体 (C-Term) (ABIN614919)

抗原

See all FGFR1 抗体
FGFR1 (Fibroblast Growth Factor Receptor 1 (FGFR1))

适用

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人, Cow, 犬

宿主

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山羊

克隆类型

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多克隆

标记

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This FGFR1 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
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    C-Term

    序列

    CLPRHPAQLA NGGLKR

    特异性

    This antibody detects CD331 / FGFR1 (C-term).

    交叉反应 (详细)

    Species reactivity (expected):Cow, DogSpecies reactivity (tested):Human

    纯化方法

    Immunoaffinity chromatography

    免疫原

    Synthetic peptide from C-term of human FGFR1 Genename: FGFR1
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 浓度

    0.5 mg/mL

    缓冲液

    Tris saline buffer, pH 7.3, 0.5 % BSA, 0.02 % sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Store at 2 - 8 °C for up to three months or (in aliquots) at -20 °C for longer.
  • 抗原

    FGFR1 (Fibroblast Growth Factor Receptor 1 (FGFR1))

    别名

    FGFR1

    背景

    The fibroblast growth factor receptor 1 belongs to the FGF Receptor subfamily. The full-length protein consists of an extracellular region, composed of three immunoglobulin-like domains, a single hydrophobic membrane-spanning segment and a cytoplasmic tyrosine kinase domain. Ligand binding results in the activation of a cascade of downstream signals, ultimately influencing mitogenesis and differentiation. Various isoforms of FGFR1 have been identified that differ in structure and specificity. Defects in FGFR1 cause craniofacial abnormalities in diseases such as Pfeiffer syndrome and Jackson-Weiss syndrome.Synonyms: BFGFR, Basic fibroblast growth factor receptor 1, CEK, FGFBR, FLG, FLT-2, FLT2, Fibroblast growth factor receptor 1, Fms-like tyrosine kinase 2, HBGFR, N-sam, Proto-oncogene c-Fgr, bFGF-R-1

    基因ID

    2260

    NCBI登录号

    NP_056934

    UniProt

    P11362

    途径

    RTK signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Sensory Perception of Sound, Stem Cell Maintenance, S100 Proteins
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