FGFR1 抗体 (C-Term)
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Quick Overview for FGFR1 抗体 (C-Term) (ABIN614919)
抗原
See all FGFR1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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序列
- CLPRHPAQLA NGGLKR
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特异性
- This antibody detects CD331 / FGFR1 (C-term).
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交叉反应 (详细)
- Species reactivity (expected):Cow, DogSpecies reactivity (tested):Human
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纯化方法
- Immunoaffinity chromatography
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免疫原
- Synthetic peptide from C-term of human FGFR1 Genename: FGFR1
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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浓度
- 0.5 mg/mL
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缓冲液
- Tris saline buffer, pH 7.3, 0.5 % BSA, 0.02 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store at 2 - 8 °C for up to three months or (in aliquots) at -20 °C for longer.
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- FGFR1 (Fibroblast Growth Factor Receptor 1 (FGFR1))
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别名
- FGFR1
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背景
- The fibroblast growth factor receptor 1 belongs to the FGF Receptor subfamily. The full-length protein consists of an extracellular region, composed of three immunoglobulin-like domains, a single hydrophobic membrane-spanning segment and a cytoplasmic tyrosine kinase domain. Ligand binding results in the activation of a cascade of downstream signals, ultimately influencing mitogenesis and differentiation. Various isoforms of FGFR1 have been identified that differ in structure and specificity. Defects in FGFR1 cause craniofacial abnormalities in diseases such as Pfeiffer syndrome and Jackson-Weiss syndrome.Synonyms: BFGFR, Basic fibroblast growth factor receptor 1, CEK, FGFBR, FLG, FLT-2, FLT2, Fibroblast growth factor receptor 1, Fms-like tyrosine kinase 2, HBGFR, N-sam, Proto-oncogene c-Fgr, bFGF-R-1
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基因ID
- 2260
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NCBI登录号
- NP_056934
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UniProt
- P11362
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途径
- RTK signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Sensory Perception of Sound, Stem Cell Maintenance, S100 Proteins
抗原
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