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SLC8A1 抗体 (AA 250-520)

SLC8A1 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6148050
发货至: 中国
  • 抗原 See all SLC8A1 抗体
    SLC8A1 (Solute Carrier Family 8 (Sodium/calcium Exchanger), Member 1 (SLC8A1))
    抗原表位
    • 16
    • 7
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 250-520
    适用
    • 34
    • 28
    • 28
    • 8
    • 7
    • 6
    • 5
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    宿主
    • 36
    克隆类型
    • 36
    多克隆
    标记
    • 12
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This SLC8A1 antibody is un-conjugated
    应用范围
    • 36
    • 19
    • 13
    • 13
    • 13
    • 4
    • 3
    • 2
    • 2
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    序列
    WVADRRLLFY KYVYKRYRAG KQRGMIIEHE GDRPSSKTEI EMDGKVVNSH VENFLDGALV LEVDERDQDD EEARREMARI LKELKQKHPD KEIEQLIELA NYQVLSQQQK SRAFYRIQAT RLMTGAGNIL KRHAADQARK AVSMHEVNTE VTENDPVSKI FFEQGTYQCL ENCGTVALTI IRRGGDLTNT VFVDFRTEDG TANAGSDYEF TEGTVVFKPG DTQKEIRVGI IDDDIFEEDE NFLVHLSNVK VSSEASEDGI LEANHVSTLA C
    交叉反应
    人, 小鼠, 大鼠
    产品特性
    Polyclonal Antibodies
    免疫原
    Recombinant fusion protein containing a sequence corresponding to amino acids 250-520 of human SLC8A1 (NP_066920.1).
    亚型
    IgG
  • 应用备注
    WB,1:1000 - 1:2000,IHC,1:50 - 1:200
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原
    SLC8A1 (Solute Carrier Family 8 (Sodium/calcium Exchanger), Member 1 (SLC8A1))
    别名
    SLC8A1 (SLC8A1 产品)
    别名
    NCX1 antibody, AI852629 antibody, AV344025 antibody, D930008O12Rik antibody, Ncx1 antibody, Ncx antibody, SLC8A1 antibody, ncx1n antibody, solute carrier family 8 member A1 antibody, solute carrier family 8 (sodium/calcium exchanger), member 1 antibody, solute carrier family 8 (sodium/calcium exchanger), member 1b antibody, sodium/calcium exchanger 1 antibody, SLC8A1 antibody, Slc8a1 antibody, slc8a1b antibody, Tsp_07038 antibody
    背景
    In cardiac myocytes, Ca(2+) concentrations alternate between high levels during contraction and low levels during relaxation. The increase in Ca(2+) concentration during contraction is primarily due to release of Ca(2+) from intracellular stores. However, some Ca(2+) also enters the cell through the sarcolemma (plasma membrane). During relaxation, Ca(2+) is sequestered within the intracellular stores. To prevent overloading of intracellular stores, the Ca(2+) that entered across the sarcolemma must be extruded from the cell. The Na(+)-Ca(2+) exchanger is the primary mechanism by which the Ca(2+) is extruded from the cell during relaxation. In the heart, the exchanger may play a key role in digitalis action. The exchanger is the dominant mechanism in returning the cardiac myocyte to its resting state following excitation.,SLC8A1,NCX1,Cancer,Signal Transduction,Endocrine & Metabolism,Neuroscience,Calcium Signaling,Cardiovascular,Hypoxia,Heart,Contractility,SLC8A1
    分子量
    104 kDa/107 kDa/108 kDa
    基因ID
    6546
    UniProt
    P32418
    途径
    Myometrial Relaxation and Contraction
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