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KIR2DL4/CD158d 抗体

KIR2DL4 适用: 人 WB, FACS, IP, Func, IF 宿主: 小鼠 Monoclonal mAb#33 unconjugated
产品编号 ABIN614805
发货至: 中国
  • 抗原 See all KIR2DL4/CD158d (KIR2DL4) 抗体
    KIR2DL4/CD158d (KIR2DL4) (Killer Cell Immunoglobulin-Like Receptor, Two Domains, Long Cytoplasmic Tail, 4 (KIR2DL4))
    适用
    • 51
    • 1
    • 1
    宿主
    • 37
    • 14
    小鼠
    克隆类型
    • 37
    • 14
    单克隆
    标记
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    • 3
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    This KIR2DL4/CD158d antibody is un-conjugated
    应用范围
    • 47
    • 26
    • 17
    • 14
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    • 7
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    Western Blotting (WB), Flow Cytometry (FACS), Immunoprecipitation (IP), Functional Studies (Func), Immunofluorescence (IF)
    特异性
    This Monoclonal antibody mAb#33 (also known as mAb 33 or 33) recognizes extracellular portion of CD158d / KIR2DL4, a 45 kDa NK cell marker. Cell surface expression and function of CD158d / KIR2DL4 depends on genotype of particular individuals.
    交叉反应 (详细)
    Species reactivity (tested):Human.
    纯化方法
    Protein-A Affinity Chromatography
    免疫原
    NK3.3 cells and KIR2DL4-Ig fusion protein
    克隆位点
    MAb#33
    亚型
    IgG1
    Top Product
    Discover our top product KIR2DL4 Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 浓度
    1.0 mg/mL
    缓冲液
    Phosphate buffered saline (PBS), pH ~7.4, 15 mM Sodium Azide
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原
    KIR2DL4/CD158d (KIR2DL4) (Killer Cell Immunoglobulin-Like Receptor, Two Domains, Long Cytoplasmic Tail, 4 (KIR2DL4))
    别名
    CD158d / KIR2DL4 (KIR2DL4 产品)
    别名
    G9P antibody, CD158D antibody, KIR103 antibody, KIR103AS antibody, KIR2DL4 antibody, killer cell immunoglobulin like receptor, two Ig domains and long cytoplasmic tail 4 antibody, killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 4 antibody, KIR2DL4 antibody
    背景
    CD158d / KIR2DL4 is a KIR family member that shares structural features with both activating and inhibitory receptors and may mediate different functions under different circumstances. It contains cytoplasmic ITIM, suggesting inhibitory function, but also transmembrane domain similar to those of activating KIRs. It has been reported that CD158d serves as an inhibitory receptor for peripheral and uterine NK cells, but its ligation with soluble mAbs (unlike immobilized mAbs) results in activation of IFN-γ secretion. CD158d also binds both membrane form and soluble form of its ligand HLA-G.Synonyms: CD158 antigen-like family member D, G9P, KIR103AS, Killer cell immunoglobulin-like receptor 2DL4, Killer cell inhibitory receptor 103AS, MHC class I NK cell receptor KIR103AS
    基因ID
    3805
    NCBI登录号
    NP_001074239
    UniProt
    Q99706
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