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KIR2DL4/CD158d 抗体 (Center)

KIR2DL4 适用: 人 WB, ICC, IHC (p), IF 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2856036
发货至: 中国
  • 抗原 See all KIR2DL4/CD158d (KIR2DL4) 抗体
    KIR2DL4/CD158d (KIR2DL4) (Killer Cell Immunoglobulin-Like Receptor, Two Domains, Long Cytoplasmic Tail, 4 (KIR2DL4))
    抗原表位
    • 15
    • 9
    • 8
    • 7
    • 3
    • 1
    • 1
    • 1
    Center
    适用
    • 51
    • 1
    • 1
    宿主
    • 36
    • 15
    克隆类型
    • 36
    • 15
    多克隆
    标记
    • 19
    • 7
    • 5
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This KIR2DL4/CD158d antibody is un-conjugated
    应用范围
    • 47
    • 27
    • 17
    • 14
    • 13
    • 13
    • 8
    • 6
    • 6
    • 5
    • 3
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunocytochemistry (ICC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)
    产品特性
    Rabbit Polyclonal antibody to KIR2DL4 (killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 4)
    KIR2DL4 antibody
    纯化方法
    Purified by antigen-affinity chromatography.
    免疫原
    Recombinant protein encompassing a sequence within the center region of human KIR2DL4. The exact sequence is proprietary.
    亚型
    IgG
    Top Product
    Discover our top product KIR2DL4 Primary Antibody
  • 应用备注
    Suggested dilution Reference ICC/IF 1:100-1:1000* IHC (Formalin-fixed paraffin-embedded sections) 1:100-1:1000* Western blot 1:500-1:3000* Not tested in other applications. *Optimal dilutions/concentrations should be determined by the researcher.Suggested dilutionReferenceICC/IF1:100-1:1000* IHC (Formalin-fixed paraffin-embedded sections)1:100-1:1000* Western blot1:500-1:3000*
    说明

    Positive Control: THP-1

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    0.9 mg/mL
    缓冲液
    0.1M Tris, 0.1M Glycine, 10 % Glycerol ( pH 7). 0.01 % Thimerosal was added as a preservative.
    储存液
    Thimerosal (Merthiolate)
    注意事项
    This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • 抗原
    KIR2DL4/CD158d (KIR2DL4) (Killer Cell Immunoglobulin-Like Receptor, Two Domains, Long Cytoplasmic Tail, 4 (KIR2DL4))
    别名
    KIR2DL4 (KIR2DL4 产品)
    别名
    G9P antibody, CD158D antibody, KIR103 antibody, KIR103AS antibody, KIR2DL4 antibody, killer cell immunoglobulin like receptor, two Ig domains and long cytoplasmic tail 4 antibody, killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 4 antibody, KIR2DL4 antibody
    背景
    Killer cell immunoglobulin-like receptors (KIRs) are transmembrane glycoproteins expressed by natural killer cells and subsets of T cells. The KIR genes are polymorphic and highly homologous and they are found in a cluster on chromosome 19q13.4 within the 1 Mb leukocyte receptor complex (LRC). The gene content of the KIR gene cluster varies among haplotypes, although several "framework" genes are found in all haplotypes (KIR3DL3, KIR3DP1, KIR3DL4, KIR3DL2). The KIR proteins are classified by the number of extracellular immunoglobulin domains (2D or 3D) and by whether they have a long (L) or short (S) cytoplasmic domain. KIR proteins with the long cytoplasmic domain transduce inhibitory signals upon ligand binding via an immune tyrosine-based inhibitory motif (ITIM), while KIR proteins with the short cytoplasmic domain lack the ITIM motif and instead associate with the TYRO protein tyrosine kinase binding protein to transduce activating signals. The ligands for several KIR proteins are subsets of HLA class I molecules, thus, KIR proteins are thought to play an important role in regulation of the immune response. This gene is one of the "framework" loci that is present on all haplotypes. Alternative splicing results in multiple transcript variants.

    Cellular Localization: Cell membrane, Single-pass type I membrane protein
    分子量
    41 kDa
    基因ID
    3805
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