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RAD51 抗体 (AA 50-150)

This anti-RAD51 antibody is a 兔 多克隆 antibody detecting RAD51 in WB. Suitable for 人. This Primary Antibody has been cited in 3+ publications.
产品编号 ABIN6146636
发货至: 中国

Quick Overview for RAD51 抗体 (AA 50-150) (ABIN6146636)

抗原

See all RAD51 抗体
RAD51 (DNA Repair Protein Homolog 1 (RAD51))

适用

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宿主

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克隆类型

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多克隆

标记

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This RAD51 antibody is un-conjugated

应用范围

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Western Blotting (WB)
  • 抗原表位

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    AA 50-150

    序列

    EAVAYAPKKE LINIKGISEA KADKILAEAA KLVPMGFTTA TEFHQRRSEI IQITTGSKEL DKLLQGGIET GSITEMFGEF RTGKTQICHT LAVTCQLPID R

    交叉反应

    人, 小鼠, 大鼠

    产品特性

    Polyclonal Antibodies

    免疫原

    A synthetic peptide corresponding to a sequence within amino acids 50-150 of human Rad51 (NP_002866.2).

    亚型

    IgG
  • 应用备注

    WB,1:500 - 1:1000

    说明

    HIGH QUALITY

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Avoid freeze / thaw cycles.
  • Wang, Sun, Zhu, Sun, Ma, Wang, Lu, Chen, Xu: "Quantitative proteomic analysis revealed changes in protein synthesis and mitochondrial functions after acute DNA damage in mouse neural stem cells." in: Neuroscience letters, Vol. 653, pp. 355-361, (2018) (PubMed).

    Li, Zhang, Chen, Guo, Zhang, Tang, Xu, Zhang, Tao, Wang, Jiang, Sun, Mao: "Impaired DNA double-strand break repair contributes to the age-associated rise of genomic instability in humans." in: Cell death and differentiation, Vol. 23, Issue 11, pp. 1765-1777, (2017) (PubMed).

    Zhang, Tang, Jiang, Mao: "The transcription factor GATA3 is required for homologous recombination repair by regulating CtIP expression." in: Oncogene, Vol. 36, Issue 36, pp. 5168-5176, (2017) (PubMed).

  • 抗原

    RAD51 (DNA Repair Protein Homolog 1 (RAD51))

    别名

    RAD51

    背景

    The protein encoded by this gene is a member of the RAD51 protein family. RAD51 family members are highly similar to bacterial RecA and Saccharomyces cerevisiae Rad51, and are known to be involved in the homologous recombination and repair of DNA. This protein can interact with the ssDNA-binding protein RPA and RAD52, and it is thought to play roles in homologous pairing and strand transfer of DNA. This protein is also found to interact with BRCA1 and BRCA2, which may be important for the cellular response to DNA damage. BRCA2 is shown to regulate both the intracellular localization and DNA-binding ability of this protein. Loss of these controls following BRCA2 inactivation may be a key event leading to genomic instability and tumorigenesis. Multiple transcript variants encoding different isoforms have been found for this gene.,RAD51,BRCC5,FANCR,HRAD51,HsRad51,HsT16930,MRMV2,RAD51A,RECA,Epigenetics & Nuclear Signaling,DNA Damage & Repair,Cell Biology & Developmental Biology,Cell Cycle,G2/M DNA Damage Checkpoint,RAD51

    分子量

    26 kDa/31 kDa/36 kDa

    基因ID

    5888

    UniProt

    Q06609

    途径

    DNA Damage Repair
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