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OCT4 抗体

POU5F1 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6145988
发货至: 中国
  • 抗原 See all OCT4 (POU5F1) 抗体
    OCT4 (POU5F1) (POU Class 5 Homeobox 1 (POU5F1))
    适用
    • 112
    • 60
    • 30
    • 7
    • 5
    • 5
    • 4
    • 4
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    宿主
    • 102
    • 23
    • 1
    • 1
    克隆类型
    • 94
    • 32
    多克隆
    标记
    • 93
    • 5
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    This OCT4 antibody is un-conjugated
    应用范围
    • 105
    • 55
    • 27
    • 21
    • 16
    • 15
    • 15
    • 14
    • 13
    • 10
    • 9
    • 5
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    交叉反应
    人, 小鼠, 大鼠
    产品特性
    Polyclonal Antibodies
    免疫原
    A synthetic peptide of human OCT4
    亚型
    IgG
    Top Product
    Discover our top product POU5F1 Primary Antibody
  • 应用备注
    WB,1:500 - 1:2000,IHC,1:50 - 1:200
    说明

    HIGH QUALITY

    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Avoid freeze / thaw cycles.
  • Hu, Xia, Wu, Li, Qi, Hu, Wei, Li, Tian, Wei, Shen, Yin, Jiang, Yuan, Qiang, Han, Peng: "NSPc1 promotes cancer stem cell self-renewal by repressing the synthesis of all-trans retinoic acid via targeting RDH16 in malignant glioma." in: Oncogene, Vol. 36, Issue 33, pp. 4706-4718, (2017) (PubMed).

    Wang, Yi, Chen, Li, Zhang, Xiong, Li, Li, Xiang: "NOR1 Suppresses Cancer Stem-Like Cells Properties of Tumor Cells via the Inhibition of the AKT-GSK-3β-Wnt/β-catenin-ALDH1A1 Signal Circuit." in: Journal of cellular physiology, Vol. 232, Issue 10, pp. 2829-2840, (2017) (PubMed).

  • 抗原
    OCT4 (POU5F1) (POU Class 5 Homeobox 1 (POU5F1))
    别名
    POU5F1 (POU5F1 产品)
    别名
    OCT3 antibody, OCT4 antibody, OTF-3 antibody, OTF3 antibody, OTF4 antibody, Oct-3 antibody, Oct-4 antibody, POU5F1 antibody, gp9 antibody, gp-9 antibody, oct4 antibody, pou2 antibody, POU-2 antibody, cb197 antibody, spg/pou2 antibody, chunp6868 antibody, wu:fd18d06 antibody, NF-A3 antibody, Oct-3/4 antibody, Oct3 antibody, Oct3/4 antibody, Oct4 antibody, Otf-3 antibody, Otf-4 antibody, Otf3 antibody, Otf3-rs7 antibody, Otf3g antibody, Otf4 antibody, POU class 5 homeobox 1 antibody, POU domain, class 5, transcription factor 3 antibody, POU domain, class 5, transcription factor 1 antibody, POU5F1 antibody, pou5f3 antibody, Pou5f1 antibody
    背景
    This gene encodes a transcription factor containing a POU homeodomain that plays a key role in embryonic development and stem cell pluripotency. Aberrant expression of this gene in adult tissues is associated with tumorigenesis. This gene can participate in a translocation with the Ewing's sarcoma gene on chromosome 21, which also leads to tumor formation. Alternative splicing, as well as usage of alternative AUG and non-AUG translation initiation codons, results in multiple isoforms. One of the AUG start codons is polymorphic in human populations. Related pseudogenes have been identified on chromosomes 1, 3, 8, 10, and 12.,POU5F1,OCT3,OCT4,OTF-3,OTF3,OTF4,Oct-3,Oct-4,Epigenetics & Nuclear Signaling,Transcription Factors,RNA Binding,Cell Biology & Developmental Biology,ESC Pluripotency and Differentiation,Stem Cells,Embryonic Stem Cells,Germline Stem Cells,POU5F1
    分子量
    30 kDa/38 kDa
    基因ID
    5460
    UniProt
    Q01860
    途径
    Stem Cell Maintenance
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