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PHLPP1 抗体 (AA 1508-1717)

PHLPP1 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6145573
发货至: 中国
  • 抗原 See all PHLPP1 抗体
    PHLPP1 (PH Domain and Leucine Rich Repeat Protein Phosphatase 1 (PHLPP1))
    抗原表位
    • 6
    • 3
    • 3
    • 2
    • 1
    • 1
    AA 1508-1717
    适用
    • 31
    • 13
    • 12
    宿主
    • 31
    克隆类型
    • 31
    多克隆
    标记
    • 17
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    This PHLPP1 antibody is un-conjugated
    应用范围
    • 14
    • 8
    • 5
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
    序列
    PAYPSEQRCM LHPICLSNSF QRQLSSATFS SAFSDNGLDS DDEEPIEGVF TNGSRVEVEV DIHCSRAKEK EKQQHLLQVP AEASDEGIVI SANEDEPGLP RKADFSAVGT IGRRRANGSV APQERSHNVI EVATDAPLRK PGGYFAAPAQ PDPDDQFIIP PELEEEVKEI MKHHQEQQQQ QQPPPPPQLQ PQLPRHYQLD QLPDYYDTPL
    交叉反应
    人, 小鼠, 大鼠
    产品特性
    Polyclonal Antibodies
    免疫原
    Recombinant fusion protein containing a sequence corresponding to amino acids 1508-1717 of human PHLPP1 (NP_919431.2).
    亚型
    IgG
  • 应用备注
    WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200
    说明

    HIGH QUALITY

    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原
    PHLPP1 (PH Domain and Leucine Rich Repeat Protein Phosphatase 1 (PHLPP1))
    别名
    PHLPP1 (PHLPP1 产品)
    别名
    PHLPP antibody, PLEKHE1 antibody, SCOP antibody, AI836256 antibody, Phlpp antibody, Plekhe1 antibody, mKIAA0606 antibody, Scop antibody, PH domain and leucine rich repeat protein phosphatase 1 antibody, PHLPP1 antibody, phlpp1 antibody, Phlpp1 antibody
    背景
    This gene encodes a member of the serine/threonine phosphatase family. The encoded protein promotes apoptosis by dephosphorylating and inactivating the serine/threonine kinase Akt, and functions as a tumor suppressor in multiple types of cancer. Increased expression of this gene may also play a role in obesity and type 2 diabetes by interfering with Akt-mediated insulin signaling.,PHLPP1,PHLPP,PLEKHE1,PPM3A,SCOP,Cancer,Tumor suppressors,Invasion and Metastasis,Signal Transduction,Kinase,Serine/threonine kinases,PI3K-Akt Signaling Pathway,Cell Biology & Developmental Biology,Apoptosis,Phosphatase of Akt,PHLPP1
    分子量
    133 kDa/184 kDa
    基因ID
    23239
    UniProt
    O60346
    途径
    PI3K-Akt Signaling, Fc-epsilon Receptor Signaling Pathway, Neurotrophin Signaling Pathway
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