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Factor VIII 抗体

F8 适用: 人 IHC (p) 宿主: 小鼠 Monoclonal n-a unconjugated
产品编号 ABIN614478
发货至: 中国
  • 抗原 See all Factor VIII (F8) 抗体
    Factor VIII (F8) (Coagulation Factor VIII (F8))
    适用
    • 95
    • 59
    • 30
    • 17
    • 9
    • 4
    • 2
    • 2
    • 1
    • 1
    宿主
    • 88
    • 21
    • 4
    • 2
    小鼠
    克隆类型
    • 95
    • 20
    单克隆
    标记
    • 50
    • 15
    • 12
    • 5
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    This Factor VIII antibody is un-conjugated
    应用范围
    • 55
    • 42
    • 39
    • 39
    • 24
    • 11
    • 10
    • 10
    • 10
    • 6
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    特异性
    This antibody recognizes full-length Human Factor VIII (F8). Does not cross-react with von Willebrand factor.
    纯化方法
    Protein G chromatography
    免疫原
    F8 antibody was raised against purified human Factor VIII.
    克隆位点
    N-a
    亚型
    IgG1
    Top Product
    Discover our top product F8 Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 浓度
    0.73 mg/mL
    缓冲液
    PBS, pH 7.4
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    -20 °C
    储存方法
    Store the antibody at -20 °C to -70 °C.
  • 抗原
    Factor VIII (F8) (Coagulation Factor VIII (F8))
    Abstract
    F8 产品
    别名
    fb61d02 antibody, wu:fb61d02 antibody, Cf-8 antibody, Cf8 antibody, FVIII antibody, AHF antibody, DXS1253E antibody, F8B antibody, F8C antibody, HEMA antibody, coagulation factor VIIi antibody, coagulation factor VIII antibody, coagulation factor VIII, procoagulant component antibody, f7i antibody, F8 antibody
    背景
    This gene encodes coagulation factor VIII, which participates in the intrinsic pathway of blood coagulation, factor VIII is a cofactor for factor IXa which, in the presence of Ca+2 and phospholipids, converts factor X to the activated form Xa. This gene produces two alternatively spliced transcripts. Transcript variant 1 encodes a large glycoprotein, isoform a, which circulates in plasma and associates with von Willebrand factor in a noncovalent complex. This protein undergoes multiple cleavage events. Transcript variant 2 encodes a putative small protein, isoform b, which consists primarily of the phospholipid binding domain of factor VIIIc. This binding domain is essential for coagulant activity. Defects in this gene results in hemophilia A, a common recessive X-linked coagulation disorder.Synonyms: AHF, Antihemophilic factor, F8C, Procoagulant component
    基因ID
    2157
    NCBI登录号
    NP_000123
    UniProt
    P00451
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