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- 抗原 See all GIPR 抗体
- GIPR (Gastric Inhibitory Polypeptide Receptor (GIPR))
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抗原表位
- AA 22-138
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This GIPR antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (IHC)
- 序列
- RAETGSKGQT AGELYQRWER YRRECQETLA AAEPPSGLAC NGSFDMYVCW DYAAPNATAR ASCPWYLPWH HHVAAGFVLR QCGSDGQWGL WRDHTQCENP EKNEAFLDQR LILERLQ
- 交叉反应
- 人, 小鼠, 大鼠
- 产品特性
- Polyclonal Antibodies
- 纯化方法
- Affinity purification
- 免疫原
- Recombinant fusion protein containing a sequence corresponding to amino acids 22-138 of human GIPR (NP_000155.1).
- 亚型
- IgG
- Top Product
- Discover our top product GIPR Primary Antibody
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- 应用备注
- WB,1:500 - 1:2000,IHC,1:50 - 1:200
- 说明
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HIGH QUALITY
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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Inactivation of the Glucose-Dependent Insulinotropic Polypeptide Receptor Improves Outcomes following Experimental Myocardial Infarction." in: Cell metabolism, Vol. 27, Issue 2, pp. 450-460.e6, (2018) (PubMed).
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Inactivation of the Glucose-Dependent Insulinotropic Polypeptide Receptor Improves Outcomes following Experimental Myocardial Infarction." in: Cell metabolism, Vol. 27, Issue 2, pp. 450-460.e6, (2018) (PubMed).
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- 抗原
- GIPR (Gastric Inhibitory Polypeptide Receptor (GIPR))
- 别名
- GIPR (GIPR 产品)
- 别名
- GIPR antibody, PGQTL2 antibody, GIP-R antibody, Gm1081 antibody, Gm160 antibody, Gippr antibody, RATGIPPR antibody, gastric inhibitory polypeptide receptor antibody, glucagon receptor antibody, GIPR antibody, LOC100303705 antibody, Gipr antibody
- 背景
- This gene encodes a G-protein coupled receptor for gastric inhibitory polypeptide (GIP), which was originally identified as an activity in gut extracts that inhibited gastric acid secretion and gastrin release, but subsequently was demonstrated to stimulate insulin release in the presence of elevated glucose. Mice lacking this gene exhibit higher blood glucose levels with impaired initial insulin response after oral glucose load. Defect in this gene thus may contribute to the pathogenesis of diabetes.,GIPR,PGQTL2,Signal Transduction,G protein signaling,G-Protein-Coupled Receptors(GPCR),Neuroscience,GIPR
- 分子量
- 48 kDa/49 kDa/53 kDa
- 基因ID
- 2696
- UniProt
- P48546
- 途径
- Positive Regulation of Peptide Hormone Secretion, cAMP Metabolic Process, Regulation of G-Protein Coupled Receptor Protein Signaling
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