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DFFB 抗体 (AA 109-338)

DFFB 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6139552
发货至: 中国
  • 抗原 See all DFFB 抗体
    DFFB (DNA Fragmentation Factor, 40kDa, beta Polypeptide (Caspase-Activated DNase) (DFFB))
    抗原表位
    • 15
    • 15
    • 14
    • 10
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 109-338
    适用
    • 55
    • 45
    • 24
    宿主
    • 72
    • 4
    克隆类型
    • 73
    • 3
    多克隆
    标记
    • 34
    • 5
    • 5
    • 5
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    This DFFB antibody is un-conjugated
    应用范围
    • 57
    • 29
    • 26
    • 26
    • 17
    • 14
    • 11
    • 10
    • 6
    • 4
    • 3
    Western Blotting (WB), Immunohistochemistry (IHC)
    序列
    DEQAPQRQRL LADLLHNVSQ NIAAETRAED PPWFEGLESR FQSKSGYLRY SCESRIRSYL REVSSYPSTV GAEAQEEFLR VLGSMCQRLR SMQYNGSYFD RGAKGGSRLC TPEGWFSCQG PFDMDSCLSR HSINPYSNRE SRILFSTWNL DHIIEKKRTI IPTLVEAIKE QDGREVDWEY FYGLLFTSEN LKLVHIVCHK KTTHKLNCDP SRIYKPQTRL KRKQPVRKRQ
    交叉反应
    人, 小鼠
    产品特性
    Polyclonal Antibodies
    纯化方法
    Affinity purification
    免疫原
    Recombinant fusion protein containing a sequence corresponding to amino acids 109-338 of human DFFB (NP_004393.1).
    亚型
    IgG
    Top Product
    Discover our top product DFFB Primary Antibody
  • 应用备注
    WB,1:200 - 1:1000,IHC,1:50 - 1:200
    说明

    HIGH QUALITY

    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原
    DFFB (DNA Fragmentation Factor, 40kDa, beta Polypeptide (Caspase-Activated DNase) (DFFB))
    别名
    DFFB (DFFB 产品)
    别名
    CAD antibody, CPAN antibody, DFF-40 antibody, DFF2 antibody, DFF40 antibody, LOC100223514 antibody, 40kDa antibody, 5730477D02Rik antibody, Didff antibody, Cad antibody, carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase antibody, DNA fragmentation factor subunit beta antibody, DNA fragmentation factor, beta polypeptide (caspase-activated DNase) antibody, DNA fragmentation factor, beta subunit antibody, CAD antibody, DFFB antibody, dffb antibody, LOC100223514 antibody, Dffb antibody
    背景
    Apoptosis is a cell death process that removes toxic and/or useless cells during mammalian development. The apoptotic process is accompanied by shrinkage and fragmentation of the cells and nuclei and degradation of the chromosomal DNA into nucleosomal units. DNA fragmentation factor (DFF) is a heterodimeric protein of 40-kD (DFFB) and 45-kD (DFFA) subunits. DFFA is the substrate for caspase-3 and triggers DNA fragmentation during apoptosis. DFF becomes activated when DFFA is cleaved by caspase-3. The cleaved fragments of DFFA dissociate from DFFB, the active component of DFF. DFFB has been found to trigger both DNA fragmentation and chromatin condensation during apoptosis. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene but the biological validity of some of these variants has not been determined.,DFFB,CAD,CPAN,DFF-40,DFF2,DFF40,Epigenetics & Nuclear Signaling,Cell Biology & Developmental Biology,Apoptosis,Cell Cycle,Death Receptor Signaling Pathway,Endocrine & Metabolism,DFFB
    分子量
    11 kDa/12 kDa/30 kDa/39 kDa
    基因ID
    1677
    UniProt
    O76075
    途径
    Apoptosis, Caspase Cascade in Apoptosis
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