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- 抗原 See all DAAM2 products
- DAAM2 (Dishevelled Associated Activator of Morphogenesis 2 (DAAM2))
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抗原表位
- AA 1-86
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This DAAM2 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunofluorescence (IF)
- 序列
- MAPRKRSHHG LGFLCCFGGS DIPEINLRDN HPLQFMEFSS PIPNAEELNI RFAELVDELD LTDKNREAMF ALPPEKKWQI YCSKKK
- 交叉反应
- 人, 小鼠, 大鼠
- 产品特性
- Polyclonal Antibodies
- 纯化方法
- Affinity purification
- 免疫原
- Recombinant fusion protein containing a sequence corresponding to amino acids 1-86 of human DAAM2 (NP_056160.2).
- 亚型
- IgG
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anti-Dishevelled Associated Activator of Morphogenesis 2 (DAAM2) (AA 1-132) antibody
DAAM2 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1D8 unconjugated
anti-Dishevelled Associated Activator of Morphogenesis 2 (DAAM2) (AA 1-86) antibodyDAAM2 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Dishevelled Associated Activator of Morphogenesis 2 (DAAM2) (AA 1-101) antibodyDAAM2 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Dishevelled Associated Activator of Morphogenesis 2 (DAAM2) (AA 1-132) antibodyDAAM2 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Dishevelled Associated Activator of Morphogenesis 2 (DAAM2) (AA 68-97) antibodyDAAM2 适用: 人 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Dishevelled Associated Activator of Morphogenesis 2 (DAAM2) (AA 68-97), (N-Term) antibodyDAAM2 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB10613 unconjugated
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- 应用备注
- WB,1:500 - 1:2000,IF,1:50 - 1:200
- 说明
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HIGH QUALITY
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- 抗原
- DAAM2 (Dishevelled Associated Activator of Morphogenesis 2 (DAAM2))
- 别名
- DAAM2 (DAAM2 产品)
- 别名
- dJ90A20A.1 antibody, 2310016D11Rik antibody, AI843643 antibody, AW557870 antibody, DAAM2 antibody, dishevelled associated activator of morphogenesis 2 antibody, DAAM2 antibody, Daam2 antibody, daam2 antibody
- 背景
- Key regulator of the Wnt signaling pathway, which is required for various processes during development, such as dorsal patterning, determination of left/right symmetry or myelination in the central nervous system. Acts downstream of Wnt ligands and upstream of beta-catenin (CTNNB1. Required for canonical Wnt signaling pathway during patterning in the dorsal spinal cord by promoting the aggregation of Disheveled (Dvl complexes, thereby clustering and formation of Wnt receptor signalosomes and potentiating Wnt activity. During dorsal patterning of the spinal cord, inhibits oligodendrocytes differentiation via interaction with PIP5K1A. Also regulates non-canonical Wnt signaling pathway. Acts downstream of PITX2 in the developing gut and is required for left/right asymmetry within dorsal mesentery: affects mesenchymal condensation by lengthening cadherin-based junctions through WNT5A and non-canonical Wnt signaling, inducing polarized condensation in the left dorsal mesentery necessary to initiate gut rotation. Together with DAAM1, required for myocardial maturation and sarcomere assembly.,DAAM2,dJ90A20A.1,Stem Cells,DAAM2
- 分子量
- 123 kDa
- 基因ID
- 23500
- UniProt
- Q86T65
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