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Claudin 18 抗体 (AA 20-80)

CLDN18 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6138681
发货至: 中国
  • 抗原 See all Claudin 18 (CLDN18) 抗体
    Claudin 18 (CLDN18)
    抗原表位
    • 5
    • 4
    • 2
    • 1
    • 1
    • 1
    AA 20-80
    适用
    • 25
    • 14
    • 7
    • 4
    • 4
    • 4
    • 4
    • 3
    • 2
    • 2
    • 1
    宿主
    • 21
    • 5
    克隆类型
    • 22
    • 4
    多克隆
    标记
    • 16
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This Claudin 18 antibody is un-conjugated
    应用范围
    • 12
    • 10
    • 9
    • 3
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB)
    序列
    GCIAATGMDM WSTQDLYDNP VTSVFQYEGL WRSCVRQSSG FTECRPYFTI LGLPAMLQAV R
    交叉反应
    人, 小鼠, 大鼠
    产品特性
    Polyclonal Antibodies
    纯化方法
    Affinity purification
    免疫原
    Recombinant fusion protein containing a sequence corresponding to amino acids 20-80 of human CLDN18 (NP_057453.1).
    亚型
    IgG
    Top Product
    Discover our top product CLDN18 Primary Antibody
  • 应用备注
    WB,1:1000 - 1:2000
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原
    Claudin 18 (CLDN18)
    别名
    CLDN18 (CLDN18 产品)
    别名
    claudin-18 antibody, CLDN18 antibody, SFTA5 antibody, SFTPJ antibody, claudin 18 L homeolog antibody, claudin 18 antibody, cldn18.L antibody, CLDN18 antibody, Cldn18 antibody
    背景
    This gene encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets, and also play critical roles in maintaining cell polarity and signal transductions. This gene is upregulated in patients with ulcerative colitis and highly overexpressed in infiltrating ductal adenocarcinomas. PKC/MAPK/AP-1 (protein kinase C/mitogen-activated protein kinase/activator protein-1) dependent pathway regulates the expression of this gene in gastric cells. Alternatively spliced transcript variants encoding different isoforms have been identified.,CLDN18,SFTA5,SFTPJ,Signal Transduction,Cell Biology & Developmental Biology,Cell Adhesion,Tight Junctions,Cytoskeleton,CLDN18
    分子量
    27 kDa
    基因ID
    51208
    UniProt
    P56856
    途径
    Cell-Cell Junction Organization, Hepatitis C
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