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Caspase 9 抗体 (AA 1-98)

This anti-Caspase 9 antibody is a 兔 多克隆 antibody detecting Caspase 9 in WB, IHC 和 IF. Suitable for 人. This Primary Antibody has been cited in 3+ publications.
产品编号 ABIN6137975
发货至: 中国

Quick Overview for Caspase 9 抗体 (AA 1-98) (ABIN6137975)

抗原

See all Caspase 9 (CASP9) 抗体
Caspase 9 (CASP9) (Caspase 9, Apoptosis-Related Cysteine Peptidase (CASP9))

适用

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宿主

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克隆类型

  • 208
  • 48
多克隆

标记

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This Caspase 9 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
  • 抗原表位

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    AA 1-98

    序列

    MDEADRRLLR RCRLRLVEEL QVDQLWDALL SRELFRPHMI EDIQRAGSGS RRDQARQLII DLETRGSQAL PLFISCLEDT GQDMLASFLR TNRQAAKL

    交叉反应

    人, 小鼠, 大鼠

    产品特性

    Polyclonal Antibodies

    纯化方法

    Affinity purification

    免疫原

    Recombinant fusion protein containing a sequence corresponding to amino acids 1-98 of human Caspase-9 (NP_001220.2).

    亚型

    IgG
  • 应用备注

    WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Avoid freeze / thaw cycles.
  • Knowlton, Fernández de Castro, Ashbrook, Gestaut, Zamora, Bauer, Forrest, Frydman, Risco, Dermody: "The TRiC chaperonin controls reovirus replication through outer-capsid folding." in: Nature microbiology, Vol. 3, Issue 4, pp. 481-493, (2018) (PubMed).

    Jiang, Liao, He, Xin, Tu, Kong, Cui, Wang, Quan, Li, Zhang, Wang: "FoxM1 Directs STAT3 Expression Essential for Human Endometrial Stromal Decidualization." in: Scientific reports, Vol. 5, pp. 13735, (2016) (PubMed).

    Wang, Hu, Liang, Zeng, Li, Yan, Yang, Liu, Wang: "Thiol peroxiredoxin, a novel allergen from Bombyx mori, modulates functions of macrophages and dendritic cells." in: American journal of translational research, Vol. 8, Issue 12, pp. 5320-5329, (2016) (PubMed).

  • 抗原

    Caspase 9 (CASP9) (Caspase 9, Apoptosis-Related Cysteine Peptidase (CASP9))

    别名

    CASP9

    背景

    This gene encodes a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein can undergo autoproteolytic processing and activation by the apoptosome, a protein complex of cytochrome c and the apoptotic peptidase activating factor 1, this step is thought to be one of the earliest in the caspase activation cascade. This protein is thought to play a central role in apoptosis and to be a tumor suppressor. Alternative splicing results in multiple transcript variants.,CASP9,APAF-3,APAF3,ICE-LAP6,MCH6,PPP1R56,caspase-9,casp9,Caspase 9,Signal Transduction,ErbB-HER Signaling Pathway,Cell Biology & Developmental Biology,Apoptosis,Caspases,Mitochondrial Control of Apoptosis,Inhibition of Apoptosis,Death Receptor Signaling Pathway,Immunology & Inflammation,Neuroscience,Neurodegenerative Diseases,Amyloid Plaque and Neurofibrillary Tangle Formation in Alzheimer's Disease,CASP9

    分子量

    17 kDa/30 kDa/36 kDa/46 kDa

    基因ID

    842

    UniProt

    P55211

    途径

    MAPK Pathway, RTK signaling, Apoptosis, Caspase Cascade in Apoptosis, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Positive Regulation of Endopeptidase Activity
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