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ULK1 抗体 (pSer555)

ULK1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6136282
发货至: 中国
  • 抗原 See all ULK1 抗体
    ULK1 (Unc-51 Like Kinase 1 (ULK1))
    抗原表位
    • 25
    • 16
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    • 14
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    • 11
    • 9
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    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
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    pSer555
    适用
    • 194
    • 77
    • 66
    • 4
    • 4
    • 4
    • 3
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    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
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    宿主
    • 197
    • 3
    • 2
    克隆类型
    • 190
    • 12
    多克隆
    标记
    • 55
    • 23
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    • 8
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    • 1
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    This ULK1 antibody is un-conjugated
    应用范围
    • 112
    • 95
    • 30
    • 26
    • 26
    • 25
    • 20
    • 12
    • 10
    • 9
    • 6
    • 2
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    • 1
    Western Blotting (WB)
    序列
    RLHSA
    交叉反应
    产品特性
    Phosphorylated Antibodies
    免疫原
    A synthetic phosphorylated peptide around S555 of human Phospho-ULK1-S555 (NP_003556.1).
    亚型
    IgG
    Top Product
    Discover our top product ULK1 Primary Antibody
  • 应用备注
    WB,1:1000 - 1:2000
    说明

    HIGH QUALITY

    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原
    ULK1 (Unc-51 Like Kinase 1 (ULK1))
    别名
    ULk1 (ULK1 产品)
    别名
    ATG1 antibody, ATG1A antibody, UNC51 antibody, Unc51.1 antibody, hATG1 antibody, si:dkey-11o18.7 antibody, ulk1 antibody, ULK1 antibody, AU041434 antibody, mKIAA0722 antibody, zgc:195008 antibody, unc-51 like autophagy activating kinase 1 antibody, unc-51 like kinase 1 antibody, unc-51 like autophagy activating kinase 1a antibody, ULK1 antibody, Ulk1 antibody, ulk1b antibody, ulk1a antibody
    背景
    Serine/threonine-protein kinase involved in autophagy in response to starvation. Acts upstream of phosphatidylinositol 3-kinase PIK3C3 to regulate the formation of autophagophores, the precursors of autophagosomes. Part of regulatory feedback loops in autophagy: acts both as a downstream effector and negative regulator of mammalian target of rapamycin complex 1 (mTORC1 via interaction with RPTOR. Activated via phosphorylation by AMPK and also acts as a regulator of AMPK by mediating phosphorylation of AMPK subunits PRKAA1, PRKAB2 and PRKAG1, leading to negatively regulate AMPK activity. May phosphorylate ATG13/KIAA0652 and RPTOR, however such data need additional evidences. Plays a role early in neuronal differentiation and is required for granule cell axon formation. May also phosphorylate SESN2 and SQSTM1 to regulate autophagy. Phosphorylates FLCN, promoting autophagy. Phosphorylates AMBRA1 in response to autophagy induction, releasing AMBRA1 from the cytoskeletal docking site to induce autophagosome nucleation.,ULK1,ATG1,ATG1A,UNC51,Unc51.1,hATG1,ULk1,Signal Transduction,Kinase,Serine/threonine kinases,PI3K-Akt Signaling Pathway,Cell Biology & Developmental Biology,Autophagy,Endocrine & Metabolism,Mitochondrial metabolism,Mitophagy fission and fusion,Neuroscience,Cardiovascular,Heart,Regulator of mTOR complex function,Regulators,Protein phosphorylation,ULk1
    分子量
    112 kDa
    基因ID
    8408
    UniProt
    O75385
    途径
    Regulation of Cell Size, Autophagy
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