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DCC 抗体

DCC 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6133664
发货至: 中国
  • 抗原 See all DCC 抗体
    DCC (Deleted in Colorectal Carcinoma (DCC))
    适用
    • 39
    • 34
    • 13
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    宿主
    • 48
    • 2
    克隆类型
    • 48
    • 2
    多克隆
    标记
    • 26
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    This DCC antibody is un-conjugated
    应用范围
    • 35
    • 24
    • 12
    • 6
    • 5
    • 1
    • 1
    Western Blotting (WB)
    交叉反应
    人, 小鼠
    产品特性
    Polyclonal Antibodies
    纯化方法
    Affinity purification
    免疫原
    A synthetic peptide of human DCC
    亚型
    IgG
    Top Product
    Discover our top product DCC Primary Antibody
  • 应用备注
    WB,1:500 - 1:1000
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原
    DCC (Deleted in Colorectal Carcinoma (DCC))
    别名
    DCC (DCC 产品)
    背景
    This gene encodes a netrin 1 receptor. The transmembrane protein is a member of the immunoglobulin superfamily of cell adhesion molecules, and mediates axon guidance of neuronal growth cones towards sources of netrin 1 ligand. The cytoplasmic tail interacts with the tyrosine kinases Src and focal adhesion kinase (FAK, also known as PTK2) to mediate axon attraction. The protein partially localizes to lipid rafts, and induces apoptosis in the absence of ligand. The protein functions as a tumor suppressor, and is frequently mutated or downregulated in colorectal cancer and esophageal carcinoma.,DCC,CRC18,CRCR1,IGDCC1,MRMV1,NTN1R1,Epigenetics & Nuclear Signaling,Cancer,Tumor suppressors,Cell Biology & Developmental Biology,Apoptosis,Neuroscience,DCC
    分子量
    158 kDa
    基因ID
    1630
    UniProt
    P43146
    途径
    Regulation of Cell Size
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