DICTYOSTELIUM,dJ393P12.2,IMD2,Protein WAVE-2,Putative Wiskott Aldrich syndrome protein family member 4,SCAR 2,SCAR,SCAR2,Suppressor of cyclic-AMP receptor (WASP family),Verprolin homology domain-containing protein 2,WASF2,WASF2,WASF4,WASP family protein member 2,WASP family protein member 4,WASP family Verprolin homologous protein 2,WASP-family protein member 2,WAVE 2,WAVE2,Wiskott-Aldrich syndrome protein family member 2,Wiskott-Aldrich syndrome protein family verprolin-homologous protein
zgc:56010 antibody, WASF2 antibody, scar2 antibody, wave2 antibody, IMD2 antibody, SCAR2 antibody, WASF4 antibody, WAVE2 antibody, dJ393P12.2 antibody, AW742646 antibody, D4Ertd13e antibody, WAS protein family, member 2 antibody, WAS protein family member 2 antibody, WAS protein family member 2 L homeolog antibody, wasf2 antibody, WASF2 antibody, wasf2.L antibody, Wasf2 antibody
背景
This gene encodes a member of the Wiskott-Aldrich syndrome protein family. The gene product is a protein that forms a multiprotein complex that links receptor kinases and actin. Binding to actin occurs through a C-terminal verprolin homology domain in all family members. The multiprotein complex serves to tranduce signals that involve changes in cell shape, motility or function. The published map location (PMID:10381382) has been changed based on recent genomic sequence comparisons, which indicate that the expressed gene is located on chromosome 1, and a pseudogene may be located on chromosome X.