DcR1 抗体 (PE)
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- 抗原 See all DcR1 (TNFRSF10C) 抗体
- DcR1 (TNFRSF10C) (Tumor Necrosis Factor Receptor Superfamily, Member 10c (TNFRSF10C))
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This DcR1 antibody is conjugated to PE
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应用范围
- Flow Cytometry (FACS), Immunoprecipitation (IP)
- 特异性
- Recognizes human CD263, a 60 Kd cell surface protein, which is otherwise known as decoy receptor 1 (DcR1). CD263 is a member of the tumor necrosis factor (TNF) receptor superfamily that binds to TNF-related apoptosis inducing ligand (TRAIL). As the receptor does not possess cytoplasmic death domains it cannot induce apoptosis, but instead plays an important role in inhibiting TRAIL-induced apoptosis. CD263 is expressed in normal tissues including heart, skeletal tissues and peripheral blood neutrophils, but weakly expressed in tumor cells. Does not inhibit DcR1 (CD263) inhibitory function in TRAIL-induced apoptosis.
- 纯化方法
- Affinity purified
- 免疫原
- DcR1-Fc Chimeric protein.
- 克隆位点
- 2B8
- 亚型
- IgG1
- Top Product
- Discover our top product TNFRSF10C Primary Antibody
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- 应用备注
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Approved: Flo (1:1 - 1:10), IP
Usage: The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested. Flow Cytometry: Use 10 μL of the suggested working dilution to label 1x10^6 cells in 100 μL. Method sheets are available on request. - 说明
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Target Species of Antibody: Human
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Distilled Water.
- 浓度
- Lot specific
- 缓冲液
- Lyophilized, PBS, pH 7.4, 0.09 % sodium azide, 1 % BSA.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C
- 储存方法
- 4°C, avoid freezing.
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- 抗原
- DcR1 (TNFRSF10C) (Tumor Necrosis Factor Receptor Superfamily, Member 10c (TNFRSF10C))
- 别名
- TNFRSF10C / TRAIL-R3 / DCR1 (TNFRSF10C 产品)
- 别名
- CD263 antibody, DCR1 antibody, DCR1-TNFR antibody, LIT antibody, TRAIL-R3 antibody, TRAILR3 antibody, TRID antibody, TNFRSF10C antibody, TNF receptor superfamily member 10c antibody, TNFRSF10C antibody
- 背景
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Name/Gene ID: TNFRSF10C
Family: TNF Receptor
Synonyms: TNFRSF10C, CD263 antigen, CD263, Cytotoxic TRAIL receptor-3, Decoy receptor 1, DCR1, DCR1-TNFR, LIT, Lymphocyte inhibitor of TRAIL, TRAIL-R3, TRAILR3, TRAIL receptor 3, TRID - 基因ID
- 8794
- 途径
- Apoptosis
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