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ERBB4 抗体

ERBB4 适用: 人, 小鼠, 大鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN5708421
发货至: 中国
  • 抗原 See all ERBB4 抗体
    ERBB4 (V-Erb-A erythroblastic Leukemia Viral Oncogene Homolog 4 (Avian) (ERBB4))
    适用
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    人, 小鼠, 大鼠
    宿主
    • 188
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    克隆类型
    • 186
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    多克隆
    标记
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    This ERBB4 antibody is un-conjugated
    应用范围
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    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    纯化方法
    Antigen affinity purified
    免疫原
    Amino acids SLSDLEQQYRALRKYYENCEVVMGNLEITSIEHNRDLSFLR from the human protein were used as the immunogen for the ERBB4 antibody.
    亚型
    IgG
    Top Product
    Discover our top product ERBB4 Primary Antibody
  • 应用备注
    Optimal dilution of the ERBB4 antibody should be determined by the researcher.\. Western Blot: 0.5-1 μg/mL,IHC (FFPE): 1-2 μg/mL
    限制
    仅限研究用
  • 缓冲液
    0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
    储存条件
    -20 °C
    储存方法
    After reconstitution, the ERBB4 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
  • 抗原
    ERBB4 (V-Erb-A erythroblastic Leukemia Viral Oncogene Homolog 4 (Avian) (ERBB4))
    别名
    ERBB4 / HER4 (ERBB4 产品)
    别名
    erbb4 antibody, si:ch211-227n20.1 antibody, Her4 antibody, c-erbB-4 antibody, HER4 antibody, p180erbB4 antibody, erb-b2 receptor tyrosine kinase 4 antibody, erb-b2 receptor tyrosine kinase 4a antibody, v-erb-a erythroblastic leukemia viral oncogene homolog 4 (avian) antibody, erb-b2 receptor tyrosine kinase 4 L homeolog antibody, receptor tyrosine-protein kinase ErbB-4 antibody, ERBB4 antibody, erbb4a antibody, erbb4 antibody, erbb4.L antibody, Tsp_13582 antibody, Erbb4 antibody
    背景
    ERBB4 (V-erb-b2 avian erythroblastic leukemia viral oncogene homolog 4) also known as ONCOGENE ERBB4 or HER4, is an enzyme that in humans is encoded by the ERBB4 gene. The HER4/ERBB4 gene is a member of the type I receptor tyrosine kinase subfamily that includes EGFR, ERBB2 and ERBB3. This gene is mapped on 2q34. ERBB4 is a single-pass type I transmembrane protein with multiple furin-like cysteine rich domains, a tyrosine kinase domain, a phosphotidylinositol-3 kinase binding site and a PDZ domainbinding motif. Furthermore, ERBB4 is a transmembrane receptor tyrosine kinase that regulates cell proliferation and differentiation. After binding its ligand, heregulin, or activation of protein kinase C by TPA, the ERBB4 ectodomain is cleaved by a metalloprotease.
    UniProt
    Q15303
    途径
    RTK signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway
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