PIK3CB 抗体 (Catalytic Subunit beta, N-Term)
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- 抗原 See all PIK3CB 抗体
- PIK3CB (Phosphoinositide-3-Kinase, Catalytic, beta Polypeptide (PIK3CB))
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抗原表位
- Catalytic Subunit beta, N-Term
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This PIK3CB antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA
- 产品特性
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Synonyms: rabbit anti-PIK3CB antibody, rabbit anti-PI3K beta antibody, Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform, PI3-kinase subunit beta, PI3K-ß, PI3Kbeta, PtdIns-3-kinase subunit beta, Phosphatidylinositol 4,5-bisphosphate 3-kinase 110 kDa catalytic subunit beta, PtdIns-3-kinase subunit p110-beta, p110beta, PIK3C1
Background: PIK3CB is a catalytic subunit of phosphoinositide-3-kinase beta. PIK3CB catalyzes the production of phosphatidylinositol-3,4,5-triphosphate by phosphorylating phosphatidylinositol (PI), phosphatidylinositol-4-phosphate (PIP) and phosphatidylinositol-4,5-bisphosphate (PIP2). Growth factors and hormones trigger this phosphorylation event, which in turn coordinates cell growth, cell cycle entry, cell migration and cell survival. PTEN reverses this process. PI3K signaling pathway is constitutively activated in human cancers that have loss of function of PTEN. Furthermore, PI3KCB down regulation can suppress cell growth in malignant gliomas. Anti-PIK3C beta Antibody is suitable for researcher in Cancer, Immunology and Nuclear Signaling research.
Gene Name: PIK3CB
- 纯化方法
- Anti-PIK3C beta was affinity purified from monospecific antiserum by immunoaffinity chromatography. This antibody is specific for human PIK3C beta protein. A BLAST analysis was used to suggest cross-reactivity with PI3K-beta based on a 100% homology from human sources with the immunizing sequence. Expect partial cross reactivity to PIK3C beta from mouse and rat (93% homology) sources. Cross-reactivity with PIK3C beta from other sources has not been determined.
- 免疫原
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Immunogen: This affinity purified PIK3C-ß antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide corresponding to an N-terminal region of human Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform.
Immunogen Type: Peptide
- 亚型
- IgG
- Top Product
- Discover our top product PIK3CB Primary Antibody
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anti-Phosphoinositide-3-Kinase, Catalytic, beta Polypeptide (PIK3CB) (AA 321-507) antibody
PIK3CB 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Phosphoinositide-3-Kinase, Catalytic, beta Polypeptide (PIK3CB) (AA 807-1070) antibodyPIK3CB 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Phosphoinositide-3-Kinase, Catalytic, beta Polypeptide (PIK3CB) (AA 524-703) antibodyPIK3CB 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Phosphoinositide-3-Kinase, Catalytic, beta Polypeptide (PIK3CB) (pSer1070) antibodyPIK3CB 适用: 人, 小鼠, 大鼠, 犬, 兔 WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Phosphoinositide-3-Kinase, Catalytic, beta Polypeptide (PIK3CB) (AA 147-256) antibodyPIK3CB 适用: 人 WB, ELISA, IHC (p), PLA 宿主: 小鼠 Monoclonal 4H2 unconjugated
anti-Phosphoinositide-3-Kinase, Catalytic, beta Polypeptide (PIK3CB) (AA 147-256) antibodyPIK3CB 适用: 人 WB, ELISA, IF, PLA 宿主: 小鼠 Monoclonal 10D5 unconjugated
anti-Phosphoinositide-3-Kinase, Catalytic, beta Polypeptide (PIK3CB) (C-Term) antibodyPIK3CB 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Phosphoinositide-3-Kinase, Catalytic, beta Polypeptide (PIK3CB) (AA 771-1070) antibodyPIK3CB 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Phosphoinositide-3-Kinase, Catalytic, beta Polypeptide (PIK3CB) (AA 556-598), (Middle Region) antibodyPIK3CB 适用: 人, 小鼠, 大鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Phosphoinositide-3-Kinase, Catalytic, beta Polypeptide (PIK3CB) antibodyPIK3CB 适用: 人 WB, ELISA, IP 宿主: 兔 Monoclonal 5A9 unconjugated Recombinant Antibody
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- 应用备注
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Application Note: Anti-PIK3C beta Antibody has been tested for use in ELISA and western blotting. Specific conditions for reactivity should be optimized by the end user. Expect a band approximately 122.7 kDa in size corresponding to PI3K beta by western blotting in the appropriate cell lysate or extract.
Western Blot Dilution: 1.0 μg/mL
ELISA Dilution: 1:50,000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1.09 mg/mL
- 缓冲液
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Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2
Stabilizer: None
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 有效期
- 12 months
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- 抗原
- PIK3CB (Phosphoinositide-3-Kinase, Catalytic, beta Polypeptide (PIK3CB))
- 别名
- PIK3CB (PIK3CB 产品)
- 别名
- P110BETA antibody, PI3K antibody, PI3KBETA antibody, PIK3C1 antibody, fb92a07 antibody, wu:fb92a07 antibody, 1110001J02Rik antibody, AI447572 antibody, p110beta antibody, PI3Kbeta antibody, phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta antibody, phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta antibody, PIK3CB antibody, pik3cb antibody, Pik3cb antibody
- 基因ID
- 5291
- NCBI登录号
- NP_006210
- UniProt
- P42338
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