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PIK3CB 抗体 (Middle Region)

PIK3CB 适用: 人, 小鼠, 大鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN5518862
发货至: 中国
  • 抗原 See all PIK3CB 抗体
    PIK3CB (Phosphoinositide-3-Kinase, Catalytic, beta Polypeptide (PIK3CB))
    抗原表位
    • 16
    • 15
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    AA 556-598, Middle Region
    适用
    • 102
    • 38
    • 38
    • 18
    • 18
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
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    人, 小鼠, 大鼠
    宿主
    • 98
    • 4
    克隆类型
    • 88
    • 13
    多克隆
    标记
    • 34
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    • 5
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    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    This PIK3CB antibody is un-conjugated
    应用范围
    • 82
    • 46
    • 34
    • 26
    • 26
    • 15
    • 15
    • 6
    • 6
    • 5
    • 4
    • 2
    • 1
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    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    原理
    Rabbit IgG polyclonal antibody for Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform(PIK3CB) detection. Tested with WB, IHC-P in Human,Mouse,Rat.
    序列
    DLIWTLRQDC REIFPQSLPK LLLSIKWNKL EDVAQLQALL QIW
    交叉反应 (详细)
    No cross reactivity with other proteins.
    产品特性
    Rabbit IgG polyclonal antibody for Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform(PIK3CB) detection. Tested with WB, IHC-P in Human,Mouse,Rat.
    Gene Name: phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta
    Protein Name: Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform
    纯化方法
    Immunogen affinity purified.
    免疫原
    A synthetic peptide corresponding to a sequence in the middle region of human PIK3CB (556-598aa DLIWTLRQDCREIFPQSLPKLLLSIKWNKLEDVAQLQALLQIW), different from the related mouse and rat sequences by one amino acid.
    亚型
    IgG
    Top Product
    Discover our top product PIK3CB Primary Antibody
  • 应用备注
    WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Mouse, Rat
    IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Human, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
    Notes: Tested Species: Species with positive results. Other applications have not been tested. Optimal dilutions should be determined by end users.
    说明

    Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
    浓度
    500 μg/mL
    缓冲液
    Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    At -20°C for one year. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
  • Mu, Ma, Shi, Zhen: "The expression of S100B protein in serum of patients with brain metastases from small-cell lung cancer and its clinical significance." in: Oncology letters, Vol. 14, Issue 6, pp. 7107-7110, (2017) (PubMed).

    Wang, Sun, Li, Dong, Li, Zhao: "Resveratrol attenuates intermittent hypoxia-induced insulin resistance in rats: involvement of Sirtuin 1 and the phosphatidylinositol-4,5-bisphosphate 3-kinase/AKT pathway." in: Molecular medicine reports, Vol. 11, Issue 1, pp. 151-8, (2014) (PubMed).

  • 抗原
    PIK3CB (Phosphoinositide-3-Kinase, Catalytic, beta Polypeptide (PIK3CB))
    别名
    PIK3CB (PIK3CB 产品)
    别名
    P110BETA antibody, PI3K antibody, PI3KBETA antibody, PIK3C1 antibody, fb92a07 antibody, wu:fb92a07 antibody, 1110001J02Rik antibody, AI447572 antibody, p110beta antibody, PI3Kbeta antibody, phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta antibody, phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta antibody, PIK3CB antibody, pik3cb antibody, Pik3cb antibody
    背景
    Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta isoform is an enzyme that in humans is encoded by the PIK3CB gene. This gene encodes an isoform of the catalytic subunit of phosphoinositide 3-kinase (PI3K). These kinases are important in signaling pathways involving receptors on the outer membrane of eukaryotic cells and are named for their catalytic subunit. The encoded protein is the catalytic subunit for PI3Kbeta (PI3KB). PI3KB has been shown to be part of the activation pathway in neutrophils which have bound immune complexes at sites of injury or infection. Alternative splicing results in multiple transcript variants.

    Synonyms: p110 BETA | p110Beta | PI3K | PI3K beta | PI3K-beta | PI3Kbeta | PI3KCB | PIK3C1 | Pik3cb | P42338
    基因ID
    5291
    UniProt
    P42338
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