TTI1 抗体
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- 抗原 See all TTI1 抗体
- TTI1 (TELO2 Interacting Protein 1 (TTI1))
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This TTI1 antibody is un-conjugated
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应用范围
- ELISA, Western Blotting (WB), Immunoprecipitation (IP)
- 免疫原
- KIAA0406
- 亚型
- IgG
- Top Product
- Discover our top product TTI1 Primary Antibody
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- 应用备注
- WB:1:500-1:5000,IP:1:500-1:5000
- 说明
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HeLa cells were subjected to SDS PAGE followed by western blot with FNab09093( KIAA0406 Antibody) at dilution of 1:1000
- 限制
- 仅限研究用
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- 缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze / thaw cycles.
- 储存条件
- -20 °C
- 有效期
- 12 months
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- 抗原
- TTI1 (TELO2 Interacting Protein 1 (TTI1))
- 别名
- TTI1 (TTI1 产品)
- 别名
- KIAA0406 antibody, smg-10 antibody, 2610036D13Rik antibody, AI449463 antibody, RGD1562582 antibody, TELO2 interacting protein 1 antibody, TTI1 antibody, Tti1 antibody
- 背景
- Synonyms:TELO2-interacting protein 1 homolog,KIAA0406, SMG10,TTI1 Background:Regulator of the DNA damage response(DDR). Part of the TTT complex that is required to stabilize protein levels of the phosphatidylinositol 3-kinase-related protein kinase(PIKK) family proteins. The TTT complex is involved in the cellular resistance to DNA damage stresses, like ionizing radiation(IR), ultraviolet(UV) and mitomycin C(MMC). Together with the TTT complex and HSP90 may participate in the proper folding of newly synthesized PIKKs. Promotes assembly, stabilizes and maintains the activity of mTORC1 and mTORC2 complexes, which regulate cell growth and survival in response to nutrient and hormonal signals.
- 分子量
- 130kDa
- 基因ID
- 9675
- UniProt
- O43156
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