TTI1 抗体
(TELO2 Interacting Protein 1 (TTI1))
Regulator of the DNA damage response (DDR). Part of the TTT complex that is required to stabilize protein levels of the phosphatidylinositol 3-kinase-related protein kinase (PIKK) family proteins. The TTT complex is involved in the cellular resistance to DNA damage stresses, like ionizing radiation (IR), ultraviolet (UV) and mitomycin C (MMC). Together with the TTT complex and HSP90 may participate in the proper folding of newly synthesized PIKKs. Promotes assembly, stabilizes and maintains the activity of mTORC1 and mTORC2 complexes, which regulate cell growth and survival in response to nutrient and hormonal signals.
Recommended next Filters:
25 results
Latest Publications for our TTI1 抗体
: "A Syndromic Intellectual Disability Disorder Caused by Variants in TELO2, a Gene Encoding a Component of the TTT Complex." in: American journal of human genetics, Vol. 98, Issue 5, pp. 909-18, (2016) (PubMed).
Aliases for TTI1 抗体
TELO2 interacting protein 1 (TTI1) 抗体TELO2 interacting protein 1 (Tti1) 抗体
2610036D13Rik 抗体
AI449463 抗体
KIAA0406 抗体
RGD1562582 抗体
smg-10 抗体
您还需要查找其他产品吗？
You are here:
