THO Complex 2 抗体
THOC2
适用: 人
WB, IP, ELISA, IF
宿主: 兔
Polyclonal
unconjugated
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- 抗原 See all THO Complex 2 (THOC2) 抗体
- THO Complex 2 (THOC2)
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This THO Complex 2 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunoprecipitation (IP), ELISA, Immunofluorescence (IF)
- 免疫原
- THO complex 2
- 亚型
- IgG
- Top Product
- Discover our top product THOC2 Primary Antibody
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anti-THO Complex 2 (THOC2) (AA 101-200) antibody
THOC2 适用: 人 WB, IF (cc), IF (p), IHC (p), ELISA, IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-THO Complex 2 (THOC2) antibodyTHOC2 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
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- 缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze / thaw cycles.
- 储存条件
- -20 °C
- 有效期
- 12 months
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- 抗原
- THO Complex 2 (THOC2)
- 别名
- THOC2 (THOC2 产品)
- 别名
- RGD1561623 antibody, THO antibody, Tho2 antibody, fb73e08 antibody, fd21d11 antibody, wu:fb73e08 antibody, wu:fd21d11 antibody, si:bz1o18.2 antibody, CXorf3 antibody, THO2 antibody, dJ506G2.1 antibody, hTREX120 antibody, 6330441O12Rik antibody, D130005M13Rik antibody, Gm1139 antibody, Gm1793 antibody, THO complex 2 antibody, Thoc2 antibody, THOC2 antibody, thoc2 antibody
- 背景
- Synonyms:CXorf3 Background:Required for efficient export of polyadenylated RNA and spliced mRNA. Acts as component of the THO subcomplex of the TREX complex which is thought to couple mRNA transcription, processing and nuclear export, and which specifically associates with spliced mRNA and not with unspliced pre-mRNA. TREX is recruited to spliced mRNAs by a transcription-independent mechanism, binds to mRNA upstream of the exon-junction complex(EJC) and is recruited in a splicing-and cap-dependent manner to a region near the 5' end of the mRNA where it functions in mRNA export to the cytoplasm via the TAP/NFX1 pathway. The TREX complex is essential for the export of Kaposi's sarcoma-associated herpesvirus(KSHV) intronless mRNAs and infectious virus production. THOC2(and probably the THO complex) is involved in releasing mRNA from nuclear speckle domains. Required for NXF1 localization to the nuclear rim. Plays a role for proper neuronal development.
- 基因ID
- 57187
- UniProt
- Q8NI27
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