THO Complex 2 抗体 (AA 101-200)
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- 抗原 See all THO Complex 2 (THOC2) 抗体
- THO Complex 2 (THOC2)
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抗原表位
- AA 101-200
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This THO Complex 2 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro))
- 交叉反应
- 人
- 预测反应
- Mouse,Rat,Dog,Cow,Pig,Horse,Rabbit
- 纯化方法
- Purified by Protein A.
- 免疫原
- KLH conjugated synthetic peptide derived from human THOC2
- 亚型
- IgG
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anti-THO Complex 2 (THOC2) antibody
THOC2 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
- 有效期
- 12 months
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- 抗原
- THO Complex 2 (THOC2)
- 别名
- THOC2 (THOC2 产品)
- 别名
- RGD1561623 antibody, THO antibody, Tho2 antibody, fb73e08 antibody, fd21d11 antibody, wu:fb73e08 antibody, wu:fd21d11 antibody, si:bz1o18.2 antibody, CXorf3 antibody, THO2 antibody, dJ506G2.1 antibody, hTREX120 antibody, 6330441O12Rik antibody, D130005M13Rik antibody, Gm1139 antibody, Gm1793 antibody, THO complex 2 antibody, Thoc2 antibody, THOC2 antibody, thoc2 antibody
- 背景
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Synonyms: THO2, CXorf3, hTREX120, dJ506G2.1, THO complex subunit 2, THOC2
Background: Required for efficient export of polyadenylated RNA and spliced mRNA. Acts as component of the THO subcomplex of the TREX complex which is thought to couple mRNA transcription, processing and nuclear export, and which specifically associates with spliced mRNA and not with unspliced pre-mRNA. TREX is recruited to spliced mRNAs by a transcription-independent mechanism, binds to mRNA upstream of the exon-junction complex (EJC) and is recruited in a splicing- and cap-dependent manner to a region near the 5' end of the mRNA where it functions in mRNA export to the cytoplasm via the TAP/NFX1 pathway. The TREX complex is essential for the export of Kaposi's sarcoma-associated herpesvirus (KSHV) intronless mRNAs and infectious virus production. THOC2 (and probably the THO complex) is involved in releasing mRNA from nuclear speckle domains. Required for NXF1 localization to the nuclear rim.
- 基因ID
- 57187
- UniProt
- Q8NI27
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