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RSPO2 抗体

RSPO2 适用: 人, 小鼠, 大鼠 WB, ELISA, IP 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN5705242
发货至: 中国
  • 抗原 See all RSPO2 抗体
    RSPO2 (R-Spondin 2 (RSPO2))
    适用
    人, 小鼠, 大鼠
    宿主
    • 16
    克隆类型
    • 16
    多克隆
    标记
    • 6
    • 2
    • 2
    • 2
    • 2
    • 2
    This RSPO2 antibody is un-conjugated
    应用范围
    • 16
    • 14
    • 13
    • 13
    • 2
    • 1
    Western Blotting (WB), ELISA, Immunoprecipitation (IP)
    免疫原
    R-spondin 2 homolog (Xenopus laevis)
    亚型
    IgG
    Top Product
    Discover our top product RSPO2 Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 缓冲液
    PBS with 0.02 % sodium azide and 50 % glycerol  pH 7.3
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freeze / thaw cycles.
    储存条件
    -20 °C
    有效期
    12 months
  • 抗原
    RSPO2 (R-Spondin 2 (RSPO2))
    别名
    RSPO2 (RSPO2 产品)
    别名
    RGD1562331 antibody, CRISTIN2 antibody, 2610028F08Rik antibody, AA673245 antibody, D430027K22 antibody, ftls antibody, R-spondin 2 antibody, R-spondin 2 L homeolog antibody, Rspo2 antibody, rspo2.L antibody, rspo2 antibody, RSPO2 antibody
    背景
    Synonyms:CRISTIN2, hRspo2, R spondin 2, Roof plate specific spondin 2, RSPO2 Background:Activator of the canonical Wnt signaling pathway by acting as a ligand for LGR4-6 receptors. Upon binding to LGR4-6(LGR4, LGR5 or LGR6), LGR4-6 associate with phosphorylated LRP6 and frizzled receptors that are activated by extracellular Wnt receptors, triggering the canonical Wnt signaling pathway to increase expression of target genes. Also regulates the canonical Wnt/beta-catenin-dependent pathway and non-canonical Wnt signaling by acting as an inhibitor of ZNRF3, an important regulator of the Wnt signaling pathway. Probably also acts as a ligand for frizzled and LRP receptors.
    基因ID
    340419
    UniProt
    Q6UXX9
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