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RSPO2 抗体

RSPO2 适用: 人, 小鼠, 大鼠 WB, ELISA, IP 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7118172
发货至: 中国
  • 抗原 See all RSPO2 抗体
    RSPO2 (R-Spondin 2 (RSPO2))
    适用
    人, 小鼠, 大鼠
    宿主
    • 15
    克隆类型
    • 15
    多克隆
    标记
    • 5
    • 2
    • 2
    • 2
    • 2
    • 2
    This RSPO2 antibody is un-conjugated
    应用范围
    • 15
    • 13
    • 13
    • 13
    • 2
    Western Blotting (WB), ELISA, Immunoprecipitation (IP)
    纯化方法
    Immunogen affinity purified
    纯度
    ≥95 % as determined by SDS-PAGE
    免疫原
    R-spondin 2 homolog
    亚型
    IgG
    Top Product
    Discover our top product RSPO2 Primary Antibody
  • 应用备注
    WB: 1:500-1:3000, IP: 1:500-1:1000
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
    有效期
    12 months
  • 抗原
    RSPO2 (R-Spondin 2 (RSPO2))
    别名
    RSPO2 (RSPO2 产品)
    别名
    RGD1562331 antibody, CRISTIN2 antibody, 2610028F08Rik antibody, AA673245 antibody, D430027K22 antibody, ftls antibody, R-spondin 2 antibody, R-spondin 2 L homeolog antibody, Rspo2 antibody, rspo2.L antibody, rspo2 antibody, RSPO2 antibody
    背景
    Synonyms:CRISTIN2, hRspo2, R spondin 2, Roof plate specific spondin 2, RSPO2 Background:Activator of the canonical Wnt signaling pathway by acting as a ligand for LGR4-6 receptors. Upon binding to LGR4-6(LGR4, LGR5 or LGR6), LGR4-6 associate with phosphorylated LRP6 and frizzled receptors that are activated by extracellular Wnt receptors, triggering the canonical Wnt signaling pathway to increase expression of target genes. Also regulates the canonical Wnt/beta-catenin-dependent pathway and non-canonical Wnt signaling by acting as an inhibitor of ZNRF3, an important regulator of the Wnt signaling pathway. Probably also acts as a ligand for frizzled and LRP receptors.
    分子量
    33 kDa
    基因ID
    340419
    UniProt
    Q6UXX9
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