FBXW5 抗体
-
- 抗原 See all FBXW5 抗体
- FBXW5 (F-Box and WD Repeat Domain Containing 5 (FBXW5))
-
适用
- 人, 小鼠, 大鼠
-
宿主
- 兔
-
克隆类型
- 多克隆
-
标记
- This FBXW5 antibody is un-conjugated
-
应用范围
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
- 免疫原
- F-box and WD repeat domain containing 5
- 亚型
- IgG
- Top Product
- Discover our top product FBXW5 Primary Antibody
-
anti-F-Box and WD Repeat Domain Containing 5 (FBXW5) (AA 265-494) antibody
FBXW5 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-F-Box and WD Repeat Domain Containing 5 (FBXW5) (AA 324-350) antibodyFBXW5 适用: 人 WB 宿主: 兔 Polyclonal RB40653 unconjugated
anti-F-Box and WD Repeat Domain Containing 5 (FBXW5) (AA 1-159) antibodyFBXW5 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-F-Box and WD Repeat Domain Containing 5 (FBXW5) (AA 184-566) antibodyFBXW5 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
-
- 应用备注
- Optimal working dilution should be determined by the investigator.
- 说明
-
HEK-293 cells were subjected to SDS PAGE followed by western blot with FNab03056( FBXW5 Antibody) at dilution of 1:600
- 限制
- 仅限研究用
-
- 缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze / thaw cycles.
- 储存条件
- -20 °C
- 有效期
- 12 months
-
- 抗原
- FBXW5 (F-Box and WD Repeat Domain Containing 5 (FBXW5))
- 别名
- FBXW5 (FBXW5 产品)
- 别名
- Fbw5 antibody, AI159739 antibody, F-box and WD repeat domain containing 5 antibody, F-box and WD-40 domain protein 5 antibody, FBXW5 antibody, Fbxw5 antibody
- 背景
- Synonyms:FBW5 Background:Substrate recognition component of both SCF(SKP1-CUL1-F-box protein) and DCX(DDB1-CUL4-X-box) E3 ubiquitin-protein ligase complexes. Substrate recognition component of the SCF(FBXW5) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of SASS6 during S phase, leading to prevent centriole reduplication. The SCF(FBXW5) complex also mediates ubiquitination and degradation of actin-regulator EPS8 during G2 phase, leading to the transient degradation of EPS8 and subsequent cell shape changes required to allow mitotic progression. Substrate-specific adapter of the DCX(FBXW5) E3 ubiquitin-protein ligase complex which mediates the polyubiquitination and subsequent degradation of TSC2. May also act as a negative regulator of MAP3K7/TAK1 signaling in the interleukin-1B(IL1B) signaling pathway.
- 分子量
- 65 kDa
- 基因ID
- 54461
- UniProt
- Q969U6
-
