FBXW5 抗体 (AA 324-350)
(4 references)-
- 抗原 See all FBXW5 抗体
- FBXW5 (F-Box and WD Repeat Domain Containing 5 (FBXW5))
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抗原表位
- AA 324-350
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This FBXW5 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 纯化方法
- This antibody is purified through a protein A column, followed by peptide affinity purification.
- 免疫原
- This FBXW5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 324-350 amino acids from the Central region of human FBXW5.
- 克隆位点
- RB40653
- 亚型
- Ig Fraction
- Top Product
- Discover our top product FBXW5 Primary Antibody
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anti-F-Box and WD Repeat Domain Containing 5 (FBXW5) (AA 265-494) antibody
FBXW5 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-F-Box and WD Repeat Domain Containing 5 (FBXW5) (AA 1-159) antibodyFBXW5 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-F-Box and WD Repeat Domain Containing 5 (FBXW5) (AA 184-566) antibodyFBXW5 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- WB: 1:1000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 有效期
- 6 months
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: "New genetic associations detected in a host response study to hepatitis B vaccine." in: Genes and immunity, Vol. 11, Issue 3, pp. 232-8, (2010) (PubMed).
: "An F-box protein, FBXW5, negatively regulates TAK1 MAP3K in the IL-1beta signaling pathway." in: Biochemical and biophysical research communications, Vol. 381, Issue 3, pp. 412-7, (2009) (PubMed).
: "WD40 protein FBW5 promotes ubiquitination of tumor suppressor TSC2 by DDB1-CUL4-ROC1 ligase." in: Genes & development, Vol. 22, Issue 7, pp. 866-71, (2008) (PubMed).
: "DNA sequence and analysis of human chromosome 9. ..." in: Nature, Vol. 429, Issue 6990, pp. 369-74, (2004) (PubMed).
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: "New genetic associations detected in a host response study to hepatitis B vaccine." in: Genes and immunity, Vol. 11, Issue 3, pp. 232-8, (2010) (PubMed).
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- 抗原
- FBXW5 (F-Box and WD Repeat Domain Containing 5 (FBXW5))
- 别名
- FBXW5 (FBXW5 产品)
- 别名
- Fbw5 antibody, AI159739 antibody, F-box and WD repeat domain containing 5 antibody, F-box and WD-40 domain protein 5 antibody, FBXW5 antibody, Fbxw5 antibody
- 背景
- This gene encodes a member of the F-box protein family, members of which are characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into three classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene contains WD-40 domains, in addition to an F-box motif, so it belongs to the Fbw class. Alternatively spliced transcript variants encoding distinct isoforms have been identified for this gene, however, they were found to be nonsense-mediated mRNA decay (NMD) candidates, hence not represented.
- 分子量
- 63922
- NCBI登录号
- NP_061871
- UniProt
- Q969U6
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