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NR1H3 抗体

NR1H3 适用: 人, 小鼠, 大鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN5703097
发货至: 中国
  • 抗原 See all NR1H3 抗体
    NR1H3 (Nuclear Receptor Subfamily 1, Group H, Member 3 (NR1H3))
    适用
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    人, 小鼠, 大鼠
    宿主
    • 81
    • 9
    • 2
    克隆类型
    • 76
    • 16
    多克隆
    标记
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    This NR1H3 antibody is un-conjugated
    应用范围
    • 78
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    Western Blotting (WB), ELISA
    免疫原
    nuclear receptor subfamily 1, group H, member 3
    亚型
    IgG
    Top Product
    Discover our top product NR1H3 Primary Antibody
  • 应用备注
    WB : 1:500-1:5000
    说明

    Sp2/0 cells were subjected to SDS PAGE followed by western blot with FNab05835(NR1H3 antibody) at dilution of 1:1000

    限制
    仅限研究用
  • 缓冲液
    PBS with 0.02 % sodium azide and 50 % glycerol  pH 7.3
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freeze / thaw cycles.
    储存条件
    -20 °C
    有效期
    12 months
  • 抗原
    NR1H3 (Nuclear Receptor Subfamily 1, Group H, Member 3 (NR1H3))
    别名
    NR1H3 (NR1H3 产品)
    别名
    NR1H3 antibody, LXR-a antibody, LXRA antibody, RLD-1 antibody, AU018371 antibody, LXR antibody, RLD1 antibody, Unr1 antibody, LXRalpha antibody, LXR-alpha antibody, im:7141239 antibody, wu:fd59b01 antibody, zgc:113339 antibody, zgc:158542 antibody, nuclear receptor subfamily 1 group H member 3 antibody, nuclear receptor subfamily 1, group H, member 3 antibody, NR1H3 antibody, nr1h3 antibody, Nr1h3 antibody
    背景
    Synonyms:Liver X receptor alpha, LXR a, LXRA, NR1H3, Oxysterols receptor LXR alpha, RLD 1 Background:Nuclear receptor. Interaction with RXR shifts RXR from its role as a silent DNA-binding partner to an active ligand-binding subunit in mediating retinoid responses through target genes defined by LXRES. LXRES are DR4-type response elements characterized by direct repeats of two similar hexanuclotide half-sites spaced by four nucleotides. Plays an important role in the regulation of cholesterol homeostasis, regulating cholesterol uptake through MYLIP-dependent ubiquitination of LDLR, VLDLR and LRP8. Interplays functionally with RORA for the regulation of genes involved in liver metabolism(By similarity). Exhibits a ligand-dependent transcriptional activation activity(PubMed:25661920).
    分子量
    48 kDa
    基因ID
    10062
    UniProt
    Q13133
    途径
    Nuclear Receptor Transcription Pathway, Steroid Hormone Mediated Signaling Pathway, Nuclear Hormone Receptor Binding, Cellular Response to Molecule of Bacterial Origin, Hepatitis C
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