KHDRBS3 抗体
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- 抗原 See all KHDRBS3 抗体
- KHDRBS3 (KH Domain Containing, RNA Binding, Signal Transduction Associated 3 (KHDRBS3))
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This KHDRBS3 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
- 免疫原
- KH domain containing, RNA binding, signal transduction associated 3
- 亚型
- IgG
- Top Product
- Discover our top product KHDRBS3 Primary Antibody
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anti-KH Domain Containing, RNA Binding, Signal Transduction Associated 3 (KHDRBS3) (AA 177-346) antibody
KHDRBS3 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-KH Domain Containing, RNA Binding, Signal Transduction Associated 3 (KHDRBS3) (AA 1-346) antibodyKHDRBS3 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-KH Domain Containing, RNA Binding, Signal Transduction Associated 3 (KHDRBS3) (AA 281-330) antibodyKHDRBS3 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-KH Domain Containing, RNA Binding, Signal Transduction Associated 3 (KHDRBS3) (AA 177-346) antibodyKHDRBS3 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-KH Domain Containing, RNA Binding, Signal Transduction Associated 3 (KHDRBS3) antibodyKHDRBS3 适用: 人, 小鼠 IF 宿主: 兔 Polyclonal unconjugated
anti-KH Domain Containing, RNA Binding, Signal Transduction Associated 3 (KHDRBS3) (N-Term) antibodyKHDRBS3 适用: 人, Cow, 犬, 豚鼠, 马, 兔, Bat, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-KH Domain Containing, RNA Binding, Signal Transduction Associated 3 (KHDRBS3) (C-Term) antibodyKHDRBS3 适用: 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 马, 兔 WB, IHC 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 说明
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HepG2 cells were subjected to SDS PAGE followed by western blot with FNab04523(KHDRBS3 antibody) at dilution of 1:300
- 限制
- 仅限研究用
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- 缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze / thaw cycles.
- 储存条件
- -20 °C
- 有效期
- 12 months
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- 抗原
- KHDRBS3 (KH Domain Containing, RNA Binding, Signal Transduction Associated 3 (KHDRBS3))
- 别名
- KHDRBS3 (KHDRBS3 产品)
- 别名
- KHDRBS3 antibody, T-STAR antibody, Etle antibody, SALP antibody, SLM-2 antibody, SLM2 antibody, TSTAR antibody, etoile antibody, Slm2 antibody, KH domain containing, RNA binding, signal transduction associated 3 antibody, KH RNA binding domain containing, signal transduction associated 3 antibody, KHDRBS3 antibody, Khdrbs3 antibody
- 背景
- Synonyms:SALP, SLM2 Background:RNA-binding protein that plays a role in the regulation of alternative splicing and influences mRNA splice site selection and exon inclusion. Binds preferentially to the 5'-[AU]UAAA-3' motif in vitro. Binds optimally to RNA containing 5'-[AU]UAA-3' as a bipartite motif spaced by more than 15 nucleotides. Binds poly(A). RNA-binding abilities are down-regulated by tyrosine kinase PTK6(PubMed:10564820, PubMed:19561594, PubMed:26758068). Involved in splice site selection of vascular endothelial growth factor(PubMed:15901763). In vitro regulates CD44 alternative splicing by direct binding to purine-rich exonic enhancer(By similarity). Can regulate alternative splicing of neurexins NRXN1-3 in the laminin G-like domain 6 containing the evolutionary conserved neurexin alternative spliced segment 4(AS4) involved in neurexin selective targeting to postsynaptic partners such as neuroligins and LRRTM family members(PubMed:26758068). Targeted, cell-type specific splicing regulation of NRXN1 at AS4 is involved in neuronal glutamatergic synapse function and plasticity(By similarity). May regulate expression of KHDRBS2/SLIM-1 in defined brain neuron populations by modifying its alternative splicing(By similarity). Can bind FABP9 mRNA(By similarity). May play a role as a negative regulator of cell growth. Inhibits cell proliferation. (Microbial infection) Involved in post-transcriptional regulation of HIV-1 gene expression.
- 分子量
- 55 kDa
- 基因ID
- 10656
- UniProt
- O75525
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