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KHDRBS3 抗体 (AA 177-346)

KHDRBS3 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6142833
发货至: 中国
  • 抗原 See all KHDRBS3 抗体
    KHDRBS3 (KH Domain Containing, RNA Binding, Signal Transduction Associated 3 (KHDRBS3))
    抗原表位
    • 13
    • 10
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    AA 177-346
    适用
    • 34
    • 11
    • 10
    • 5
    • 5
    • 5
    • 4
    • 4
    • 1
    • 1
    • 1
    宿主
    • 33
    • 1
    克隆类型
    • 34
    多克隆
    标记
    • 17
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This KHDRBS3 antibody is un-conjugated
    应用范围
    • 21
    • 15
    • 4
    • 4
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF)
    序列
    GSENADVPVV RGKPTLRTRG VPAPAITRGR GGVTARPVGV VVPRGTPTPR GVLSTRGPVS RGRGLLTPRA RGVPPTGYRP PPPPPTQETY GEYDYDDGYG TAYDEQSYDS YDNSYSTPAQ SGADYYDYGH GLSEETYDSY GQEEWTNSRH KAPSARTAKG VYRDQPYGRY
    交叉反应
    人, 小鼠
    产品特性
    Polyclonal Antibodies
    免疫原
    Recombinant fusion protein containing a sequence corresponding to amino acids 177-346 of human KHDRBS3 (NP_006549.1).
    亚型
    IgG
    Top Product
    Discover our top product KHDRBS3 Primary Antibody
  • 应用备注
    WB,1:500 - 1:2000,IF,1:50 - 1:100
    说明

    HIGH QUALITY

    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原
    KHDRBS3 (KH Domain Containing, RNA Binding, Signal Transduction Associated 3 (KHDRBS3))
    别名
    KHDRBS3 (KHDRBS3 产品)
    别名
    KHDRBS3 antibody, T-STAR antibody, Etle antibody, SALP antibody, SLM-2 antibody, SLM2 antibody, TSTAR antibody, etoile antibody, Slm2 antibody, KH domain containing, RNA binding, signal transduction associated 3 antibody, KH RNA binding domain containing, signal transduction associated 3 antibody, KHDRBS3 antibody, Khdrbs3 antibody
    背景
    RNA-binding protein that plays a role in the regulation of alternative splicing and influences mRNA splice site selection and exon inclusion. Binds preferentially to the 5'-[AU]UAAA-3' motif in vitro. Binds optimally to RNA containing 5'-[AU]UAA-3' as a bipartite motif spaced by more than 15 nucleotides. Binds poly(A. RNA-binding abilities are down-regulated by tyrosine kinase PTK6. Involved in splice site selection of vascular endothelial growth factor. In vitro regulates CD44 alternative splicing by direct binding to purine-rich exonic enhancer (By similarity. Can regulate alternative splicing of neurexins NRXN1-3 in the laminin G-like domain 6 containing the evolutionary conserved neurexin alternative spliced segment 4 (AS4 involved in neurexin selective targeting to postsynaptic partners such as neuroligins and LRRTM family members. Targeted, cell-type specific splicing regulation of NRXN1 at AS4 is involved in neuronal glutamatergic synapse function and plasticity (By similarity. May regulate expression of KHDRBS2/SLIM-1 in defined brain neuron populations by modifying its alternative splicing (By similarity. Can bind FABP9 mRNA (By similarity. May play a role as a negative regulator of cell growth. Inhibits cell proliferation.,KHDRBS3,Etle,SALP,SLM-2,SLM2,T-STAR,TSTAR,etoile,Epigenetics & Nuclear Signaling,KHDRBS3
    分子量
    30 kDa/38 kDa
    基因ID
    10656
    UniProt
    O75525
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