BAP1 抗体
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- 抗原 See all BAP1 抗体
- BAP1 (BRCA1 Associated Protein-1 (Ubiquitin Carboxy-terminal Hydrolase) (BAP1))
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适用
- 人, 小鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This BAP1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA
- 免疫原
- BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase)
- 亚型
- IgG
- Top Product
- Discover our top product BAP1 Primary Antibody
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anti-BRCA1 Associated Protein-1 (Ubiquitin Carboxy-terminal Hydrolase) (BAP1) (AA 36-66) antibody
BAP1 适用: 人, 大鼠, 小鼠 WB, IHC (p), IF, FACS 宿主: 兔 Polyclonal RB4559-4560 unconjugated
anti-BRCA1 Associated Protein-1 (Ubiquitin Carboxy-terminal Hydrolase) (BAP1) (AA 460-729) antibodyBAP1 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-BRCA1 Associated Protein-1 (Ubiquitin Carboxy-terminal Hydrolase) (BAP1) antibodyBAP1 适用: 人, 大鼠, 小鼠 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-BRCA1 Associated Protein-1 (Ubiquitin Carboxy-terminal Hydrolase) (BAP1) (pSer592) antibodyBAP1 适用: 大鼠 ELISA, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-BRCA1 Associated Protein-1 (Ubiquitin Carboxy-terminal Hydrolase) (BAP1) antibodyBAP1 适用: 人, 大鼠, 小鼠 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-BRCA1 Associated Protein-1 (Ubiquitin Carboxy-terminal Hydrolase) (BAP1) (AA 1-729) antibodyBAP1 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-BRCA1 Associated Protein-1 (Ubiquitin Carboxy-terminal Hydrolase) (BAP1) (AA 191-326) antibodyBAP1 适用: 人 ELISA, Coat 宿主: 小鼠 Monoclonal BAP1-2431 unconjugated
anti-BRCA1 Associated Protein-1 (Ubiquitin Carboxy-terminal Hydrolase) (BAP1) antibodyBAP1 适用: 人, 大鼠, 小鼠 WB, IHC, IF, IC 宿主: 兔 Polyclonal unconjugated
anti-BRCA1 Associated Protein-1 (Ubiquitin Carboxy-terminal Hydrolase) (BAP1) (AA 36-66) antibodyBAP1 适用: 人, 小鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-BRCA1 Associated Protein-1 (Ubiquitin Carboxy-terminal Hydrolase) (BAP1) (AA 460-729) antibodyBAP1 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
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- 缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze / thaw cycles.
- 储存条件
- -20 °C
- 有效期
- 12 months
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- 抗原
- BAP1 (BRCA1 Associated Protein-1 (Ubiquitin Carboxy-terminal Hydrolase) (BAP1))
- 别名
- BAP1 (BAP1 产品)
- 别名
- HUCEP-13 antibody, UCHL2 antibody, BAIAP3 antibody, 2300006C11Rik antibody, AA989761 antibody, AW553466 antibody, mKIAA0272 antibody, uch-x4 antibody, hucep-13 antibody, hucep-6 antibody, uchl2 antibody, si:dkey-42i9.9 antibody, BRCA1 associated protein 1 antibody, Brca1 associated protein 1 antibody, BRCA1 associated protein 1 L homeolog antibody, BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase) antibody, BAP1 antibody, Bap1 antibody, bap1.L antibody, bap1 antibody
- 背景
- Synonyms:BAP1, BRCA1 associated protein 1, Cerebral protein 6, HUCEP 13, hucep 6, KIAA0272, UCHL2 Background:Deubiquitinating enzyme that plays a key role in chromatin by mediating deubiquitination of histone H2A and HCFC1. Catalytic component of the PR-DUB complex, a complex that specifically mediates deubiquitination of histone H2A monoubiquitinated at 'Lys-119'(H2AK119ub1). Does not deubiquitinate monoubiquitinated histone H2B. Acts as a regulator of cell growth by mediating deubiquitination of HCFC1 N-terminal and C-terminal chains, with some specificity toward 'Lys-48'-linked polyubiquitin chains compared to 'Lys-63'-linked polyubiquitin chains. Deubiquitination of HCFC1 does not lead to increase stability of HCFC1. Interferes with the BRCA1 and BARD1 heterodimer activity by inhibiting their ability to mediate ubiquitination and autoubiquitination. It however does not mediate deubiquitination of BRCA1 and BARD1. Able to mediate autodeubiquitination via intramolecular interactions to couteract monoubiquitination at the nuclear localization signal(NLS), thereby protecting it from cytoplasmic sequestration(PubMed:24703950). Acts as a tumor suppressor.
- 分子量
- 91 kDa
- 基因ID
- 8314
- UniProt
- Q92560
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