BAP1 抗体 (AA 191-326)
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北京 101111
Quick Overview for BAP1 抗体 (AA 191-326) (ABIN6940957)
抗原
See all BAP1 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 191-326
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原理
- BAP1 (BRCA1 Associated Protein 1) Antibody
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特异性
- The BAP1 gene belongs to the ubiquitin C-terminal hydrolase subfamily of de-ubiquitination enzymes that are involved in the removal of ubiquitin from proteins. The encoded enzyme binds to the breast cancer type 1 susceptibility protein (BRCA1) via the RING finger domain of the latter and acts as a tumor suppressor. In addition, the enzyme may be involved in regulation of transcription, regulation of cell cycle and growth, response to DNA damage and chromatin dynamics. Germ line mutations in this gene may be associated with tumor predisposition syndrome (TPDS), which involves increased risk of cancers including malignant mesothelioma, Uveal melanoma and cutaneous melanoma.
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纯化方法
- 200ug/ml of Ab Purified from Bioreactor Concentrate by Protein A/G.
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免疫原
- Recombinant human BAP1 protein fragment (around aa 191-326) (exact sequence is proprietary)
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亚型
- IgG2c, kappa
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anti-BRCA1 Associated Protein-1 (Ubiquitin Carboxy-terminal Hydrolase) (BAP1) (AA 475-525) antibody
BAP1 适用: 人, 小鼠 WB, IHC, IP, ICC 宿主: 兔 Monoclonal BLR372N unconjugated Recombinant Antibody
anti-BRCA1 Associated Protein-1 (Ubiquitin Carboxy-terminal Hydrolase) (BAP1) (AA 475-525) antibodyBAP1 适用: 人, 小鼠 WB, IHC, IP, ICC 宿主: 兔 Monoclonal BLR372N unconjugated Recombinant Antibody
anti-BRCA1 Associated Protein-1 (Ubiquitin Carboxy-terminal Hydrolase) (BAP1) (AA 36-66) antibodyBAP1 适用: 人, 小鼠, 大鼠 WB, IF, IHC (p), FACS 宿主: 兔 Polyclonal RB4559-4560 unconjugated
anti-BRCA1 Associated Protein-1 (Ubiquitin Carboxy-terminal Hydrolase) (BAP1) (AA 460-729) antibodyBAP1 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-BRCA1 Associated Protein-1 (Ubiquitin Carboxy-terminal Hydrolase) (BAP1) antibodyBAP1 适用: 人, 小鼠, 大鼠 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-BRCA1 Associated Protein-1 (Ubiquitin Carboxy-terminal Hydrolase) (BAP1) (pSer592) antibodyBAP1 适用: 大鼠 ELISA, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-BRCA1 Associated Protein-1 (Ubiquitin Carboxy-terminal Hydrolase) (BAP1) (AA 1-729) antibodyBAP1 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-BRCA1 Associated Protein-1 (Ubiquitin Carboxy-terminal Hydrolase) (BAP1) antibodyKO Validated BAP1 适用: 人 WB 宿主: 兔 Monoclonal 25GB3670 unconjugated Recombinant Antibody
anti-BRCA1 Associated Protein-1 (Ubiquitin Carboxy-terminal Hydrolase) (BAP1) (AA 679-729) antibodyBAP1 适用: 人 WB, IP, IHC (fp) 宿主: 兔 Polyclonal unconjugated
anti-BRCA1 Associated Protein-1 (Ubiquitin Carboxy-terminal Hydrolase) (BAP1) antibodyBAP1 适用: 人, 小鼠, 大鼠 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
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应用备注
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Positive Control: Jurkat or PC-3 or HepG2 cells. Testis, Placenta, Ovarian or Breast Carcinoma.
Known Application: ELISA (For coating, order Ab without BSA), Optimal dilution for a specific application should be determined.
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限制
- 仅限研究用
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浓度
- 200 μg/mL
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缓冲液
- Prepared in 10 mM PBS with 0.05 % BSA & 0.05 % azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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储存方法
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
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有效期
- 24 months
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- BAP1 (BRCA1 Associated Protein-1 (Ubiquitin Carboxy-terminal Hydrolase) (BAP1))
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别名
- BAP1
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背景
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BAP1, BRCA1 associated protein 1, Cerebral protein 13, Cerebral protein 6, HUCEP 13, Hucep 6, HUCEP13, Hucep6, TPDS, Ubiquitin carboxy terminal hydrolase, Ubiquitin carboxyl terminal hydrolase BAP1, UCHL2
Jurkat or PC-3 or HepG2 cells. Testis, Ovarian or Breast Carcinoma., Placenta
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分子量
- 91kDa
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基因ID
- 8314, 106674
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UniProt
- Q92560
抗原
-
