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PRKG1 抗体

PRKG1 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN5700509
发货至: 中国
  • 抗原 See all PRKG1 抗体
    PRKG1 (Protein Kinase, CGMP-Dependent, Type I (PRKG1))
    适用
    • 43
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    • 1
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    宿主
    • 37
    • 6
    克隆类型
    • 39
    • 4
    多克隆
    标记
    • 25
    • 3
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    • 2
    • 1
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    This PRKG1 antibody is un-conjugated
    应用范围
    • 36
    • 24
    • 16
    • 7
    • 3
    • 3
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA
    免疫原
    protein kinase, cGMP-dependent, type I
    亚型
    IgG
    Top Product
    Discover our top product PRKG1 Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 缓冲液
    PBS with 0.02 % sodium azide and 50 % glycerol  pH 7.3
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freeze / thaw cycles.
    储存条件
    -20 °C
    有效期
    12 months
  • 抗原
    PRKG1 (Protein Kinase, CGMP-Dependent, Type I (PRKG1))
    别名
    PRKG1 (PRKG1 产品)
    别名
    prkg1 antibody, zgc:63955 antibody, Pkgi antibody, cGk1 antibody, 1 antibody, PKG antibody, PRKG1B antibody, PRKGR1B antibody, cGK antibody, cGK 1 antibody, cGK1 antibody, cGKI antibody, cGKI-BETA antibody, cGKI-alpha antibody, CGKI antibody, cGKI-beta antibody, AW125416 antibody, Gm19690 antibody, Prkg1b antibody, Prkgr1b antibody, Prkg1beta antibody, protein kinase, cGMP-dependent, type Ia antibody, protein kinase, cGMP-dependent, type I antibody, protein kinase, cGMP-dependent, type 1 antibody, prkg1a antibody, PRKG1 antibody, prkg1 antibody, Prkg1 antibody
    背景
    Synonyms:PRKG1B, PRKGR1A, PRKGR1B Background:Mammals have three different isoforms of cyclic GMP-dependent protein kinase (Ialpha, Ibeta, and II). These PRKG isoforms act as key mediators of the nitric oxide/cGMP signaling pathway and are important components of many signal transduction processes in diverse cell types. This PRKG1 gene on human chromosome 10 encodes the soluble Ialpha and Ibeta isoforms of PRKG by alternative transcript splicing. A separate gene on human chromosome 4, PRKG2, encodes the membrane-bound PRKG isoform II. The PRKG1 proteins play a central role in regulating cardiovascular and neuronal functions in addition to relaxing smooth muscle tone, preventing platelet aggregation, and modulating cell growth. This gene is most strongly expressed in all types of smooth muscle, platelets, cerebellar Purkinje cells, hippocampal neurons, and the lateral amygdala. Isoforms Ialpha and Ibeta have identical cGMP-binding and catalytic domains but differ in their leucine/isoleucine zipper and autoinhibitory sequences and therefore differ in their dimerization substrates and kinase enzyme activity.
    基因ID
    5592
    UniProt
    Q13976
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