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- 抗原 See all PRKG1 抗体
- PRKG1 (Protein Kinase, CGMP-Dependent, Type I (PRKG1))
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抗原表位
- Center
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适用
- 人, 小鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This PRKG1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 产品特性
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Rabbit Polyclonal antibody to cGK1 (protein kinase, cGMP-dependent, type I)
cGK1 antibody - 纯化方法
- Purified by antigen-affinity chromatography.
- 免疫原
- Recombinant protein encompassing a sequence within the center region of human cGK1. The exact sequence is proprietary.
- 亚型
- IgG
- Top Product
- Discover our top product PRKG1 Primary Antibody
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anti-Protein Kinase, CGMP-Dependent, Type I (PRKG1) (AA 629-660), (C-Term) antibody
PRKG1 适用: 人, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal RB1046 unconjugated
anti-Protein Kinase, CGMP-Dependent, Type I (PRKG1) (AA 73-170) antibodyPRKG1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 5E5 unconjugated
anti-Protein Kinase, CGMP-Dependent, Type I (PRKG1) (AA 73-170) antibodyPRKG1 适用: 人 WB, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 2B3 unconjugated
anti-Protein Kinase, CGMP-Dependent, Type I (PRKG1) antibodyPRKG1 适用: 人, 小鼠, 大鼠, Pig, Cow, 小鸡, 犬 IF (cc) 宿主: 兔 Polyclonal unconjugated
anti-Protein Kinase, CGMP-Dependent, Type I (PRKG1) antibodyPRKG1 适用: 人, 小鼠, 大鼠, Pig WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Protein Kinase, CGMP-Dependent, Type I (PRKG1) (AA 1-312) antibodyPRKG1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Protein Kinase, CGMP-Dependent, Type I (PRKG1) (AA 73-171) antibodyPRKG1 适用: 人 WB, IHC, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 2B3 unconjugated
anti-Protein Kinase, CGMP-Dependent, Type I (PRKG1) (AA 657-671) antibodyPRKG1 适用: 人, 小鼠, 大鼠, Pig, Cow, 小鸡, 犬, Bat, 马, 猴, 兔 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Protein Kinase, CGMP-Dependent, Type I (PRKG1) antibodyPRKG1 适用: 人 WB, IF, FACS 宿主: 小鼠 Monoclonal 9A4 unconjugated
anti-Protein Kinase, CGMP-Dependent, Type I (PRKG1) (AA 629-660) antibodyPRKG1 适用: 人, 小鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- Suggested dilution Reference IHC (Formalin-fixed paraffin-embedded sections) 1:100-1:1000* Western blot 1:500-1:3000* Not tested in other applications. *Optimal dilutions/concentrations should be determined by the researcher.Suggested dilutionReferenceIHC (Formalin-fixed paraffin-embedded sections)1:100-1:1000* Western blot1:500-1:3000*
- 说明
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Positive Control: NIH-3T3 , JC
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- 0.1M Tris, 0.1M Glycine, 10 % Glycerol ( pH 7). 0.01 % Thimerosal was added as a preservative.
- 储存液
- Thimerosal (Merthiolate)
- 注意事项
- This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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- 抗原
- PRKG1 (Protein Kinase, CGMP-Dependent, Type I (PRKG1))
- 别名
- cGK1 (PRKG1 产品)
- 别名
- prkg1 antibody, zgc:63955 antibody, Pkgi antibody, cGk1 antibody, 1 antibody, PKG antibody, PRKG1B antibody, PRKGR1B antibody, cGK antibody, cGK 1 antibody, cGK1 antibody, cGKI antibody, cGKI-BETA antibody, cGKI-alpha antibody, CGKI antibody, cGKI-beta antibody, AW125416 antibody, Gm19690 antibody, Prkg1b antibody, Prkgr1b antibody, Prkg1beta antibody, protein kinase, cGMP-dependent, type Ia antibody, protein kinase, cGMP-dependent, type I antibody, protein kinase, cGMP-dependent, type 1 antibody, prkg1a antibody, PRKG1 antibody, prkg1 antibody, Prkg1 antibody
- 背景
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Mammals have three different isoforms of cyclic GMP-dependent protein kinase (Ialpha, Ibeta, and II). These PRKG isoforms act as key mediators of the nitric oxide/cGMP signaling pathway and are important components of many signal transduction processes in diverse cell types. This PRKG1 gene on human chromosome 10 encodes the soluble Ialpha and Ibeta isoforms of PRKG by alternative transcript splicing. A separate gene on human chromosome 4, PRKG2, encodes the membrane-bound PRKG isoform II. The PRKG1 proteins play a central role in regulating cardiovascular and neuronal functions in addition to relaxing smooth muscle tone, preventing platelet aggregation, and modulating cell growth. This gene is most strongly expressed in all types of smooth muscle, platelets, cerebellar Purkinje cells, hippocampal neurons, and the lateral amygdala. Isoforms Ialpha and Ibeta have identical cGMP-binding and catalytic domains but differ in their leucine/isoleucine zipper and autoinhibitory sequences and therefore differ in their dimerization substrates and kinase enzyme activity. [provided by RefSeq, Sep 2011]
- 分子量
- 76 kDa
- 基因ID
- 5592
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