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BAX 抗体

This anti-BAX antibody is a 兔 多克隆 antibody detecting BAX in WB, IHC 和 ELISA. Suitable for 人, 小鼠, 大鼠 和 猴.
产品编号 ABIN5700358
发货至: 中国

Quick Overview for BAX 抗体 (ABIN5700358)

抗原

See all BAX 抗体
BAX (BCL2-Associated X Protein (BAX))

适用

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人, 小鼠, 大鼠, 猴

宿主

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  • 94
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  • 1

克隆类型

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  • 88
多克隆

标记

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This BAX antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC), ELISA
  • 免疫原

    BCL2-associated X protein

    亚型

    IgG
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    说明

    HEK-293 cells were subjected to SDS PAGE followed by western blot with FNab00809(BAX antibody) at dilution of 1:1000

    限制

    仅限研究用
  • 缓冲液

    PBS with 0.02 % sodium azide and 50 % glycerol  pH 7.3

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze / thaw cycles.

    储存条件

    -20 °C

    有效期

    12 months
  • 抗原

    BAX (BCL2-Associated X Protein (BAX))

    别名

    BAX

    背景

    Synonyms:BCL2L4, Apoptosis regulator BAX, BAX Background:The protein encoded by this gene belongs to the BCL2 protein family. BCL2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. This protein forms a heterodimer with BCL2, and functions as an apoptotic activator. This protein is reported to interact with, and increase the opening of, the mitochondrial voltage-dependent anion channel (VDAC), which leads to the loss in membrane potential and the release of cytochrome c. The expression of this gene is regulated by the tumor suppressor P53 and has been shown to be involved in P53-mediated apoptosis. Multiple alternatively spliced transcript variants, which encode different isoforms, have been reported for this gene.

    分子量

    21 kDa

    基因ID

    581

    UniProt

    Q07812

    途径

    p53 Pathway, PI3K-Akt Signaling, Apoptosis, Caspase Cascade in Apoptosis, Positive Regulation of Endopeptidase Activity, Unfolded Protein Response
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