SNX27 抗体
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- 抗原 See all SNX27 抗体
- SNX27 (Sorting Nexin 27 (SNX27))
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This SNX27 antibody is un-conjugated
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应用范围
- ELISA, Western Blotting (WB), Immunohistochemistry (IHC)
- 免疫原
- sorting nexin family member 27
- 亚型
- IgG
- Top Product
- Discover our top product SNX27 Primary Antibody
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anti-Sorting Nexin 27 (SNX27) (AA 458-497) antibody
SNX27 适用: 人 ELISA, WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Sorting Nexin 27 (SNX27) (C-Term) antibodySNX27 适用: 人, 小鼠, 大鼠, Cow, 斑马鱼, 兔, 犬, 豚鼠, 马 WB 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 说明
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Jurkat cells were subjected to SDS PAGE followed by western blot with FNab08090(SNX27 antibody) at dilution of 1:1200
- 限制
- 仅限研究用
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- 缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze / thaw cycles.
- 储存条件
- -20 °C
- 有效期
- 12 months
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- 抗原
- SNX27 (Sorting Nexin 27 (SNX27))
- 别名
- SNX27 (SNX27 产品)
- 别名
- MRT1 antibody, MY014 antibody, 5730552M22Rik antibody, ESTM45 antibody, ESTM47 antibody, R75405 antibody, mKIAA0488 antibody, Mrt1 antibody, sorting nexin family member 27 antibody, SNX27 antibody, Snx27 antibody
- 背景
- Synonyms:KIAA0488 Background:Involved in the retrograde transport from endosome to plasma membrane, a trafficking pathway that promotes the recycling of internalized transmembrane proteins. Following internalization, endocytosed transmembrane proteins are delivered to early endosomes and recycled to the plasma membrane instead of being degraded in lysosomes. SNX27 specifically binds and directs sorting of a subset of transmembrane proteins containing a PDZ-binding motif at the C-terminus: following interaction with target transmembrane proteins, associates with the retromer complex, preventing entry into the lysosomal pathway, and promotes retromer-tubule based plasma membrane recycling. SNX27 also binds with the WASH complex. Interacts with membranes containing phosphatidylinositol-3-phosphate(PtdIns(3P)). May participate in establishment of natural killer cell polarity. Recruits CYTIP to early endosomes.
- 基因ID
- 81609
- UniProt
- Q96L92
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