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- 抗原 See all SNX27 抗体
- SNX27 (Sorting Nexin 27 (SNX27))
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抗原表位
- AA 458-497
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This SNX27 antibody is un-conjugated
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应用范围
- ELISA, Western Blotting (WB), Immunohistochemistry (IHC)
- 交叉反应
- 人
- 纯化方法
- >95%, Protein G purified
- 免疫原
- Recombinant Human Sorting nexin-27 protein (458-497AA)
- 亚型
- IgG
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anti-Sorting Nexin 27 (SNX27) (C-Term) antibody
SNX27 适用: 人, 小鼠, 大鼠, Cow, 斑马鱼, 犬, 豚鼠, 马, 兔 WB 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- Recommended dilution: WB:1:500-1:5000, IHC:1:20-1:200,
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4 - 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- 抗原
- SNX27 (Sorting Nexin 27 (SNX27))
- 别名
- SNX27 (SNX27 产品)
- 别名
- MRT1 antibody, MY014 antibody, 5730552M22Rik antibody, ESTM45 antibody, ESTM47 antibody, R75405 antibody, mKIAA0488 antibody, Mrt1 antibody, sorting nexin family member 27 antibody, SNX27 antibody, Snx27 antibody
- 背景
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Background: Involved in the retrograde transport from endosome to plasma membrane, a trafficking pathway that promotes the recycling of internalized transmembrane proteins. Following internalization, endocytosed transmembrane proteins are delivered to early endosomes and recycled to the plasma membrane instead of being degraded in lysosomes. SNX27 specifically binds and directs sorting of a subset of transmembrane proteins containing a PDZ-binding motif at the C-terminus: following interaction with target transmembrane proteins, associates with the retromer complex, preventing entry into the lysosomal pathway, and promotes retromer-tubule based plasma membrane recycling. SNX27 also binds with the WASH complex. Interacts with membranes containing phosphatidylinositol-3-phosphate (PtdIns(3P)). May participate in establishment of natural killer cell polarity. Recruits CYTIP to early endosomes.
Aliases: KIAA0488 antibody, Methamphetamine responsive transcript 1 antibody, MGC126871 antibody, MGC126873 antibody, MGC20471 antibody, MRT1 antibody, MY014 antibody, OTTHUMP00000042487 antibody, RP11-98D18.12 antibody, SNX27 antibody, SNX27_HUMAN antibody, Sorting nexin family member 27 antibody, Sorting nexin-27 antibody
- UniProt
- Q96L92
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