DTX3L 抗体
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- 抗原 See all DTX3L 抗体
- DTX3L (Deltex E3 ubiquitin ligase 3L (DTX3L))
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This DTX3L antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA
- 免疫原
- deltex 3-like (Drosophila)
- 亚型
- IgG
- Top Product
- Discover our top product DTX3L Primary Antibody
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anti-Deltex E3 ubiquitin ligase 3L (DTX3L) (AA 3-110) antibody
DTX3L 适用: 人 WB, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 1D10 unconjugated
anti-Deltex E3 ubiquitin ligase 3L (DTX3L) (AA 651-740) antibodyDTX3L 适用: 人, 小鼠, 大鼠 ELISA, FACS, IF (cc), IF (p), IHC (p), IHC (fro), ICC 宿主: 兔 Polyclonal unconjugated
anti-Deltex E3 ubiquitin ligase 3L (DTX3L) (AA 3-110) antibodyDTX3L 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Deltex E3 ubiquitin ligase 3L (DTX3L) antibodyDTX3L 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
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- 缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze / thaw cycles.
- 储存条件
- -20 °C
- 有效期
- 12 months
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- 抗原
- DTX3L (Deltex E3 ubiquitin ligase 3L (DTX3L))
- 别名
- DTX3L (DTX3L 产品)
- 别名
- BBAP antibody, RGD1565144 antibody, AU042200 antibody, BC023741 antibody, DTX3L antibody, deltex E3 ubiquitin ligase 3L antibody, deltex 3-like, E3 ubiquitin ligase antibody, probable E3 ubiquitin-protein ligase DTX3 antibody, DTX3L antibody, Dtx3l antibody, LOC100521724 antibody
- 背景
- Synonyms:BBAP Background:Ubiquitin ligase that mediates monoubiquitination of 'Lys-91' of histone H4(H4K91ub1), in response to DNA damage. Protects cells exposed to DNA-damaging agents. The exact role of H4K91ub1 in DNA damage response is still unclear but it may function as a licensing signal for additional histone H4 post-translational modifications such as H4 'Lys-20' methylation(H4K20me). Involved in the recruitment of 53BP1/TP53BP1 to sites of DNA damage by mediating H4K91ub1 formation. In concert with PARP9, plays a role in PARP1-dependent DNA damage repair. PARP1-dependent PARP9-DTX3L-mediated ubiquitination promotes the rapid and specific recruitment of 53BP1/TP53BP1, UIMC1/RAP80, and BRCA1 to DNA damage sites.
- 分子量
- 84 kDa
- 基因ID
- 151636
- UniProt
- Q8TDB6
- 途径
- Notch Signaling
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